DRSC/TRiP Functional Genomics Resources

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Protein Alignment ham and ZNF696

DIOPT Version :9

Sequence 1:NP_724130.4 Gene:ham / 35135 FlyBaseID:FBgn0045852 Length:1108 Species:Drosophila melanogaster
Sequence 2:NP_112157.2 Gene:ZNF696 / 79943 HGNCID:25872 Length:374 Species:Homo sapiens


Alignment Length:753 Identity:128/753 - (16%)
Similarity:191/753 - (25%) Gaps:418/753 - (55%)


- Green bases have known domain annotations that are detailed below.


  Fly   268 AAAAAAAAAVVAASSSGAKSGGGGSSAPSDDRSDRDNGSL-YSGDEFSKDKKNSSLIREGDIDFT 331
            :|...||.:...|:.:||..|.|....|     .|..||| ...::.::::...|  ..|.:  |
Human    37 SAEVQAAQSTEPAAEAGAPEGEGHRGGP-----PRALGSLGLCENQEARERPGGS--PRGPV--T 92

  Fly   332 DDENG--FDIRCEVCDKVYPDLDLLDDHLIGAHHFKQDEFPCKQCALRFCHRPLLIKHEAISHNN 394
            .::.|  ..:..:|.....|..:       |...:|...|||..|...|.......||.:| |:.
Human    93 SEKTGGQSGLESDVPPNAGPGAE-------GGGSWKGRPFPCGACGRSFKCSSDAAKHRSI-HSG 149

  Fly   395 IRKYSCENCSKVFCDPSNLQRHIRAYHVGARCHPCPECGKTFGTSSGLKQHQHIHSSVKPFACEV 459
            .:.|.|.:|.|.|...|::.||.|| |.|.|.:.|.||||.||.|..|.:||.:|:..||:||..
Human   150 EKPYECSDCGKAFIHSSHVVRHQRA-HSGERPYACAECGKAFGQSFNLLRHQRVHTGEKPYACAD 213

  Fly   460 CSKAYTQFSNLCRHKRMHATCRMQIKCDKCNQSFSTLTSLTKHKKFCDSTGPGPYRNQHVNRHHQ 524
            |.||:.|.|:..:|:|.|...|: ..|.:|.:.|...:::.:|::               ..|.:
Human   214 CGKAFGQRSDAAKHRRTHTGERL-YACGECGKRFLHSSNVVRHRR---------------THHGE 262

  Fly   525 HPHQHPLPHQPHLAATATSTCPAPPRESSESSSSAAAAAVAAMSTPPNPFLMFRTAPSFFPGFPP 589
            :|::                |    ||                                      
Human   263 NPYE----------------C----RE-------------------------------------- 269

  Fly   590 YGFPPFLPQNPLHPTNIPMFFSKNPMDLGCGGPEITSPVSAFDQKLPFGFLKGENSESQAYDKVT 654
                                         ||                                  
Human   270 -----------------------------CG---------------------------------- 271

  Fly   655 EKELVFKAEEKLKKEPLVQAFEGEEDESRSSLDIKGKLEDTRNDSKSEEQDDMKQEPERVSTPDQ 719
                              |||      |:||                                  
Human   272 ------------------QAF------SQSS---------------------------------- 278

  Fly   720 QQAEDDRKSIDIMSTPPPADTPSGGDGPLDLSICRKRSAGSFFTAPAEDNLMLHRFMPRLHEFEA 784
                                                             ||:.|           
Human   279 -------------------------------------------------NLLQH----------- 283

  Fly   785 ERGQPLKMRKSHSSAESSTSQKSHKGSSPTPTPTASPGLTPSPSPPTSAGGELSSTSEGGAVPTM 849
                                |:.|.|..|                                    
Human   284 --------------------QRVHTGERP------------------------------------ 292

  Fly   850 AAAAFAADHSALASGPTLPQTHPTFHPLLLEEIYRSGFPFLCQPGGRRGIEALLAGAASAAAPKR 914
                                                                             
Human   293 ----------------------------------------------------------------- 292

  Fly   915 PLPPVKFSAGSVVGLKTKDRYSCKFCGKVFPRSANLTRHLRTHTGEQPYPCKYCDRAFSISSNLQ 979
                                ::|:.||:.|.||:.|..|.|.||||:|:.|.:|.|||...|...
Human   293 --------------------FACQDCGRAFSRSSFLREHRRIHTGEKPHQCGHCGRAFRALSGFF 337

  Fly   980 RHVRNIHNKERPFRCELCDRSFGQQTNLDRHVKKHESE 1017
            ||.| :|..|:||||..|.|:|....:|.:|.:.|.:|
Human   338 RHQR-LHTGEKPFRCTECGRAFRLSFHLIQHRRVHGAE 374

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hamNP_724130.4 PR-SET_ZFPM 131..253 CDD:380978
C2H2 Zn finger 341..363 CDD:275368 3/21 (14%)
C2H2 Zn finger 371..392 CDD:275368 6/20 (30%)
SFP1 <391..479 CDD:227516 38/87 (44%)
C2H2 Zn finger 400..421 CDD:275368 9/20 (45%)
SUF4-like 403..>445 CDD:411020 20/41 (49%)
C2H2 Zn finger 403..421 CDD:411020 8/17 (47%)
C2H2 Zn finger 429..449 CDD:275368 11/19 (58%)
C2H2 Zn finger 457..477 CDD:275368 8/19 (42%)
C2H2 Zn finger 486..504 CDD:275368 4/17 (24%)
PTZ00121 <641..>728 CDD:173412 6/86 (7%)
COG5048 935..>1028 CDD:227381 36/83 (43%)
zf-C2H2 935..957 CDD:395048 9/21 (43%)
C2H2 Zn finger 937..957 CDD:275368 9/19 (47%)
zf-H2C2_2 949..973 CDD:404364 12/23 (52%)
C2H2 Zn finger 965..986 CDD:275368 9/20 (45%)
C2H2 Zn finger 994..1014 CDD:275368 6/19 (32%)
ZNF696NP_112157.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 30..119 20/97 (21%)
COG5048 <124..340 CDD:227381 92/613 (15%)
C2H2 Zn finger 127..147 CDD:275368 6/20 (30%)
zf-H2C2_2 142..162 CDD:290200 8/20 (40%)
C2H2 Zn finger 155..175 CDD:275368 9/20 (45%)
zf-H2C2_2 167..190 CDD:290200 12/23 (52%)
C2H2 Zn finger 183..203 CDD:275368 11/19 (58%)
zf-H2C2_2 195..218 CDD:290200 10/22 (45%)
C2H2 Zn finger 211..231 CDD:275368 8/19 (42%)
zf-H2C2_2 226..248 CDD:290200 7/22 (32%)
C2H2 Zn finger 239..259 CDD:275368 4/34 (12%)
zf-H2C2_2 251..276 CDD:290200 11/184 (6%)
C2H2 Zn finger 267..287 CDD:275368 15/262 (6%)
zf-H2C2_2 279..304 CDD:290200 11/176 (6%)
C2H2 Zn finger 295..315 CDD:275368 9/19 (47%)
zf-H2C2_2 308..330 CDD:290200 11/21 (52%)
C2H2 Zn finger 323..343 CDD:275368 9/20 (45%)
zf-H2C2_2 338..358 CDD:290200 11/20 (55%)
C2H2 Zn finger 351..371 CDD:275368 6/19 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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