DRSC/TRiP Functional Genomics Resources

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Protein Alignment ham and ZNF580

DIOPT Version :9

Sequence 1:NP_724130.4 Gene:ham / 35135 FlyBaseID:FBgn0045852 Length:1108 Species:Drosophila melanogaster
Sequence 2:NP_001156895.1 Gene:ZNF580 / 51157 HGNCID:29473 Length:172 Species:Homo sapiens


Alignment Length:204 Identity:58/204 - (28%)
Similarity:78/204 - (38%) Gaps:47/204 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   823 LTPSPSPPTSAGGELSSTSEGGAVPTMAAAAFAADHSALASGPTLPQ--TH--------PTFHPL 877
            |.|.|..|.|:..|........|.|...|...::..|: |:||..|:  .|        |..:.:
Human     4 LPPRPPHPRSSSPEAMDPPPPKAPPFPKAEGPSSTPSS-AAGPRPPRLGRHLLIDANGVPYTYTV 67

  Fly   878 LLEEIYRSGFPFLCQPGGRRGIEALLAGAASAAAPKRPLPPVKFSAGSVVGLKTKDRYSCKFCGK 942
            .|||          :|.|               .|:|..||.:  .|...|      |||..|.:
Human    68 QLEE----------EPRG---------------PPQREAPPGE--PGPRKG------YSCPECAR 99

  Fly   943 VFPRSANLTRHLRTHTGEQPYPCKYCDRAFSISSNLQRHVRNIHNKER--PFRCELCDRSFGQQT 1005
            ||.....|..|..:|:..:|:.|..|.:||..||:|.|| |..|....  |..|.||.|.|....
Human   100 VFASPLRLQSHRVSHSDLKPFTCGACGKAFKRSSHLSRH-RATHRARAGPPHTCPLCPRRFQDAA 163

  Fly  1006 NLDRHVKKH 1014
            .|.:||:.|
Human   164 ELAQHVRLH 172

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hamNP_724130.4 PR-SET_ZFPM 131..253 CDD:380978
C2H2 Zn finger 341..363 CDD:275368
C2H2 Zn finger 371..392 CDD:275368
SFP1 <391..479 CDD:227516
C2H2 Zn finger 400..421 CDD:275368
SUF4-like 403..>445 CDD:411020
C2H2 Zn finger 403..421 CDD:411020
C2H2 Zn finger 429..449 CDD:275368
C2H2 Zn finger 457..477 CDD:275368
C2H2 Zn finger 486..504 CDD:275368
PTZ00121 <641..>728 CDD:173412
COG5048 935..>1028 CDD:227381 31/82 (38%)
zf-C2H2 935..957 CDD:395048 8/21 (38%)
C2H2 Zn finger 937..957 CDD:275368 6/19 (32%)
zf-H2C2_2 949..973 CDD:404364 7/23 (30%)
C2H2 Zn finger 965..986 CDD:275368 10/20 (50%)
C2H2 Zn finger 994..1014 CDD:275368 8/19 (42%)
ZNF580NP_001156895.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..93 27/122 (22%)
C2H2 Zn finger 94..114 CDD:275368 6/19 (32%)
zf-C2H2 120..142 CDD:395048 10/22 (45%)
C2H2 Zn finger 122..142 CDD:275368 10/20 (50%)
C2H2 Zn finger 152..172 CDD:275368 8/19 (42%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.000

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