Protein Alignment ham and ZNF727

DIOPT Version :9

• Sequence 1: NP_724130.4
• Gene: ham / 35135
• FlyBaseID: FBgn0045852
• Length: 1108
• Species: Drosophila melanogaster
• Sequence 2: NP_001152994.1
• Gene: ZNF727 / 442319
• HGNCID: 22785
• Length: 499
• Species: Homo sapiens
• Alignment Length: 248
• Identity: 80/248 - (32%)
• Similarity: 113/248 - (45%)
• Gaps: 30/248 - (12%)

  Fly   298 DRSDRDNGSLYSGDEFSKDKKNSSLIREGDIDFTDDENGFDIRCEVCDKVYPDLDLLDDHLIGAH 362
            |||       |..:|..|..|..|.:.|.:...|..:   ..:||.|.|.:.....|..|  ..:
Human   197 DRS-------YKCEECGKACKKFSNLTEHNRVHTGKK---PYKCEECGKTFTCSSALTKH--KRN 249

  Fly   363 HFKQDEFPCKQC--ALRFCHRPLLIKHEAISHNNIRKYSCENCSKVFCDPSNLQRHIRAYHVGAR 425
            |.....:.|::|  |.|.|..  |.||:.| |...:.|.|:.|.|.|...|:|.:|.| .|.|.:
Human   250 HTGDRPYKCEECHKAFRCCSD--LTKHKRI-HTGEKPYKCKECHKAFRCCSDLTKHKR-IHTGEK 310

  Fly   426 CHPCPECGKTFGTSSGLKQHQHIHSSVKPFACEVCSKAYTQFSNLCRHKRMHATCRMQIKCDKCN 490
            .:.|.||||.|...|.|.||..||:..||:.||.|.||:|..|.|..|||:|...| ..||::|.
Human   311 PYKCNECGKAFMWISALSQHNRIHTGEKPYICEECGKAFTYSSTLISHKRIHMELR-PYKCEECG 374

  Fly   491 QSFSTLTSLTKHKKFCDSTGPGPYRNQHVNR---------HHQHPHQHPLPHQ 534
            ::|...:.||.||:.  .||..||:.:...:         .|:..|....|::
Human   375 KTFKWFSDLTNHKRI--HTGEKPYKCEECGKSFTCSSNLIKHKRIHMEVRPYK 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ham	NP_724130.4	PR-SET_ZFPM	131..253	CDD:380978
		C2H2 Zn finger	341..363	CDD:275368	6/21 (29%)
		C2H2 Zn finger	371..392	CDD:275368	9/22 (41%)
		SFP1	<391..479	CDD:227516	38/87 (44%)
		C2H2 Zn finger	400..421	CDD:275368	8/20 (40%)
		SUF4-like	403..>445	CDD:411020	17/41 (41%)
		C2H2 Zn finger	403..421	CDD:411020	7/17 (41%)
		C2H2 Zn finger	429..449	CDD:275368	10/19 (53%)
		C2H2 Zn finger	457..477	CDD:275368	11/19 (58%)
		C2H2 Zn finger	486..504	CDD:275368	6/17 (35%)
		PTZ00121	<641..>728	CDD:173412
		COG5048	935..>1028	CDD:227381
		zf-C2H2	935..957	CDD:395048
		C2H2 Zn finger	937..957	CDD:275368
		zf-H2C2_2	949..973	CDD:404364
		C2H2 Zn finger	965..986	CDD:275368
		C2H2 Zn finger	994..1014	CDD:275368
ZNF727	NP_001152994.1	KRAB	4..64	CDD:214630
		KRAB	4..43	CDD:279668
		C2H2 Zn finger	148..167	CDD:275370
		C2H2 Zn finger	175..194	CDD:275368
		C2H2 Zn finger	202..222	CDD:275368	5/19 (26%)
		zf-H2C2_2	214..239	CDD:290200	6/27 (22%)
		COG5048	<226..409	CDD:227381	67/194 (35%)
		C2H2 Zn finger	230..250	CDD:275368	6/21 (29%)
		zf-H2C2_2	242..267	CDD:290200	6/26 (23%)
		C2H2 Zn finger	258..278	CDD:275368	9/22 (41%)
		zf-H2C2_2	270..295	CDD:290200	10/27 (37%)
		C2H2 Zn finger	286..306	CDD:275368	8/20 (40%)
		zf-H2C2_2	298..321	CDD:290200	10/23 (43%)
		C2H2 Zn finger	314..334	CDD:275368	10/19 (53%)
		zf-H2C2_2	326..351	CDD:290200	12/24 (50%)
		C2H2 Zn finger	342..362	CDD:275368	11/19 (58%)
		C2H2 Zn finger	370..390	CDD:275368	7/21 (33%)
		zf-H2C2_2	382..407	CDD:290200	8/26 (31%)
		C2H2 Zn finger	398..418	CDD:275368	1/19 (5%)
		C2H2 Zn finger	426..446	CDD:275368	80/248 (32%)
		zf-H2C2_2	438..463	CDD:290200
		C2H2 Zn finger	454..474	CDD:275368

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.000