Protein Alignment ham and ZNF506

DIOPT Version :9

• Sequence 1: NP_724130.4
• Gene: ham / 35135
• FlyBaseID: FBgn0045852
• Length: 1108
• Species: Drosophila melanogaster
• Sequence 2: NP_001092739.1
• Gene: ZNF506 / 440515
• HGNCID: 23780
• Length: 444
• Species: Homo sapiens
• Alignment Length: 240
• Identity: 76/240 - (31%)
• Similarity: 112/240 - (46%)
• Gaps: 33/240 - (13%)

  Fly   308 YSGDEFSKDKKNSS------LIREGDIDFTDDENGFDIRCEVCDKVYPDLDLLDDHLIGAHHFKQ 366
            |..:|..|..|.||      .|..|:..:         :||.|.|.|.....|..|.|  .|..:
Human   201 YKCEECGKAYKQSSHLTTHKKIHTGEKPY---------KCEECGKAYKQSCNLTTHKI--IHTGE 254

  Fly   367 DEFPCKQCALRFCHRPLLIKHEAISHNNIRKYSCENCSKVFCDPSNLQRHIRAYHVGARCHPCPE 431
            ..:.|::|...|.|...|..|:.| |...:.|.|:.|.|.|...|.|.:| ...|.|.:.:.|.|
Human   255 KPYRCRECGKAFNHPATLFSHKKI-HTGEKPYKCDKCGKAFISSSTLTKH-EIIHTGEKPYKCEE 317

  Fly   432 CGKTFGTSSGLKQHQHIHSSVKPFACEVCSKAYTQFSNLCRHKRMHATCRMQIKCDKCNQSFSTL 496
            |||.|..||.|.:|:.||:...|:.|:.|.|.:|.:|:|.:|||.| |.....||::|.::|:..
Human   318 CGKAFNRSSNLTKHKRIHTGDVPYKCDECGKTFTWYSSLSKHKRAH-TGEKPYKCEECGKAFTAF 381

  Fly   497 TSLTKHKKFCDSTGPGPYR----------NQHVNRHHQ-HPHQHP 530
            ::||:||..  .||..||:          :..:|:|.: |..|.|
Human   382 STLTEHKII--HTGEKPYKCEECGKAFNWSSALNKHKKIHIRQKP 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ham	NP_724130.4	PR-SET_ZFPM	131..253	CDD:380978
		C2H2 Zn finger	341..363	CDD:275368	8/21 (38%)
		C2H2 Zn finger	371..392	CDD:275368	7/20 (35%)
		SFP1	<391..479	CDD:227516	34/87 (39%)
		C2H2 Zn finger	400..421	CDD:275368	7/20 (35%)
		SUF4-like	403..>445	CDD:411020	17/41 (41%)
		C2H2 Zn finger	403..421	CDD:411020	6/17 (35%)
		C2H2 Zn finger	429..449	CDD:275368	10/19 (53%)
		C2H2 Zn finger	457..477	CDD:275368	9/19 (47%)
		C2H2 Zn finger	486..504	CDD:275368	6/17 (35%)
		PTZ00121	<641..>728	CDD:173412
		COG5048	935..>1028	CDD:227381
		zf-C2H2	935..957	CDD:395048
		C2H2 Zn finger	937..957	CDD:275368
		zf-H2C2_2	949..973	CDD:404364
		C2H2 Zn finger	965..986	CDD:275368
		C2H2 Zn finger	994..1014	CDD:275368
ZNF506	NP_001092739.1	KRAB	4..62	CDD:214630
		KRAB	6..43	CDD:279668
		C2H2 Zn finger	147..167	CDD:275368
		C2H2 Zn finger	175..195	CDD:275368
		C2H2 Zn finger	203..223	CDD:275368	5/19 (26%)
		zf-H2C2_2	215..240	CDD:290200	7/33 (21%)
		C2H2 Zn finger	231..251	CDD:275368	8/21 (38%)
		zf-H2C2_2	243..268	CDD:290200	7/26 (27%)
		COG5048	<255..417	CDD:227381	56/166 (34%)
		C2H2 Zn finger	259..279	CDD:275368	7/20 (35%)
		zf-H2C2_2	272..296	CDD:290200	9/24 (38%)
		C2H2 Zn finger	287..307	CDD:275368	7/20 (35%)
		zf-H2C2_2	300..324	CDD:290200	10/24 (42%)
		C2H2 Zn finger	315..335	CDD:275368	10/19 (53%)
		zf-H2C2_2	327..351	CDD:290200	8/23 (35%)
		C2H2 Zn finger	343..363	CDD:275368	9/19 (47%)
		zf-H2C2_2	355..379	CDD:290200	9/24 (38%)
		C2H2 Zn finger	371..391	CDD:275368	7/21 (33%)
		zf-H2C2_2	384..407	CDD:290200	8/24 (33%)
		C2H2 Zn finger	399..419	CDD:275368	2/19 (11%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.000