DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ham and CG12071

DIOPT Version :9

Sequence 1:NP_724130.4 Gene:ham / 35135 FlyBaseID:FBgn0045852 Length:1108 Species:Drosophila melanogaster
Sequence 2:NP_651832.3 Gene:CG12071 / 43660 FlyBaseID:FBgn0039808 Length:581 Species:Drosophila melanogaster


Alignment Length:588 Identity:96/588 - (16%)
Similarity:181/588 - (30%) Gaps:236/588 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly   651 DKVT--EKELVFKAEEKLKKEPLVQAFEGEEDESRSSLDIKGKLEDTRNDSKSEEQDDMKQEPER 713
            ||:|  :|....:|...::::....|.:.::.::..    :.......|::.|:...:|:|:.::
  Fly     2 DKMTVAQKNAYLEAHMAVQQQMAQAAIQFKQQQTSQ----QQNSPTANNNNNSQNNGNMQQQQQQ 62

  Fly   714 VSTPDQQQAEDDRKSIDIMSTPPPADTPSGGDGPLDLSICRKRSAGSFFTAPAEDNLMLHRFMPR 778
            .....|||.:..::.....:...|..:.|        ::....:..|.||.| :|.:..      
  Fly    63 QQQQQQQQQQQQQQQHYAATIKVPQISSS--------NVAAAAAGESTFTVP-DDGMGF------ 112

  Fly   779 LHEFEAERG-QPLKMRKSHSSAESSTSQKSHKGSSPTPTPTASPGLTPSPSPPTSAGGELSSTSE 842
                  |.| :.|:...:.|:||..|..            ...|.|.|...|..          |
  Fly   113 ------EGGVRVLQSLGTWSAAEQLTYN------------IPKPNLIPFTEPYV----------E 149

  Fly   843 GGAVPTMAAAAFAADHSALASGPTLPQTHPTFHPLLLEEIYRSGFPFLCQPGGRRGIEALLAGAA 907
            ||::                        ||......|:::.:                       
  Fly   150 GGSM------------------------HPASRLKALQQVQQ----------------------- 167

  Fly   908 SAAAPKRPLPPVKFSAGSVVGLKTKDRYSCKFCGKVFPRSANLTRHLRTHTGEQPYPCKYCDRAF 972
             |::..|...|.|         .|...:.|..|||...|...||.|:|.||||:||.|:.|::||
  Fly   168 -ASSGVRKTNPSK---------STNKAFECTVCGKGLARKDKLTIHMRIHTGEKPYICEVCNKAF 222

  Fly   973 S------ISSNLQRHV---------RNIHN----KERP--------------------------- 991
            :      |..|..:||         :.::|    ||:|                           
  Fly   223 ARRDKLVIHMNKFKHVTPTNIAPLGKRLNNMVKKKEQPDPPPEDNKQSLELQLQQQAVQVAAQNI 287

  Fly   992 -------------------------FRCELCDRSFGQQTNLDRHVKKH----ESE---GNNFRDS 1024
                                     :.||||.|.|..:.....|.|.|    :.|   ..:.:.:
  Fly   288 IVQSAQGAPTSIPGIIIPHHQQQLSWTCELCGRMFSSRDEWSIHAKSHLEYXQPERLVAESTKPA 352

  Fly  1025 PSSSGIAEREEYFDDIRKFM----------------NRVYTPNSLAGN-----EGDTEEYP---- 1064
            .:::|:..:....::.|.:.                .::...|.:..|     :...:::|    
  Fly   353 AAAAGVIAKTTSSNNSRNYQMDANQNQIQMEAQARKQKIIIQNQMILNASHQQQQQPQQHPQQQQ 417

  Fly  1065 -------------------------NSDDQSVNLEKDSGNFNNNSSNISNNNSSSGNN-NNSSKA 1103
                                     ....|....::........|:.:.||||||.:| ||.|:.
  Fly   418 HQQQQQQHVAHGKKAARKHQQHLQQQQQQQQQQQQQQQQQQQQTSAPMYNNNSSSNHNGNNQSQE 482

  Fly  1104 ITI 1106
            :::
  Fly   483 VSV 485

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hamNP_724130.4 PR-SET_ZFPM 131..253 CDD:380978
C2H2 Zn finger 341..363 CDD:275368
C2H2 Zn finger 371..392 CDD:275368
SFP1 <391..479 CDD:227516
C2H2 Zn finger 400..421 CDD:275368
SUF4-like 403..>445 CDD:411020
C2H2 Zn finger 403..421 CDD:411020
C2H2 Zn finger 429..449 CDD:275368
C2H2 Zn finger 457..477 CDD:275368
C2H2 Zn finger 486..504 CDD:275368
PTZ00121 <641..>728 CDD:173412 13/78 (17%)
COG5048 935..>1028 CDD:227381 37/170 (22%)
zf-C2H2 935..957 CDD:395048 9/21 (43%)
C2H2 Zn finger 937..957 CDD:275368 9/19 (47%)
zf-H2C2_2 949..973 CDD:404364 13/23 (57%)
C2H2 Zn finger 965..986 CDD:275368 8/35 (23%)
C2H2 Zn finger 994..1014 CDD:275368 8/19 (42%)
CG12071NP_651832.3 zf-C2H2 185..207 CDD:278523 9/21 (43%)
C2H2 Zn finger 187..207 CDD:275368 9/19 (47%)
zf-H2C2_2 200..224 CDD:290200 14/23 (61%)
C2H2 Zn finger 215..232 CDD:275368 5/16 (31%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24393
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.100

Return to query results.
Submit another query.