DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ham and CG17328

DIOPT Version :9

Sequence 1:	NP_724130.4	Gene:	ham / 35135	FlyBaseID:	FBgn0045852	Length:	1108	Species:	Drosophila melanogaster
Sequence 2:	NP_609786.2	Gene:	CG17328 / 34962	FlyBaseID:	FBgn0028895	Length:	413	Species:	Drosophila melanogaster

Alignment Length:	275	Identity:	69/275 - (25%)
Similarity:	101/275 - (36%)	Gaps:	75/275 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   341 CEVCDKVYPDLDLLDDHLIGAHHFKQDEFPCKQCALRFCHRPLLIKHEAISHNNIRKYSCENCSK 405
            |..|.|.:..:..|..|:  ..|..:..:.|..|..||..:..|..||. :|...:.:.||.|||
  Fly   149 CYECHKSFKCIAQLTQHI--RTHTGEKPYQCSFCIQRFAQKYNLKVHER-THTGDKPFQCEICSK 210

  Fly   406 VFCDPSNLQRHIRAYHVGARCHPCPECGKTFGTSSGLKQHQHIHSSVKPFACEVCSKAYTQFSNL 470
            .|....|.|.| :..|:|.|...|..|.|.|.|:..|.:|...|:.:|...|:||.||:::..::
  Fly   211 QFSALGNFQAH-QKIHLGVRDQVCSLCQKGFYTAGDLSKHMITHTGIKNHHCDVCGKAFSRRRDM 274

  Fly   471 CRHK-RMH---------------------------ATCRMQIKCDKCNQSFSTLTSLTKHKKFCD 507
            ..|| ::|                           .......||..|:::|.|..||:.|
  Fly   275 RTHKLKLHPLESSTNHDIVDDDDDEAIDTDPVGLDTLDHAHFKCPDCDKAFDTADSLSLH----- 334

  Fly   508 STGPGPYRNQHVNR--------------HHQHPHQHPLPHQPHLAATATSTCPAPPRESSESSSS 558
                  :|....|.              ||.|   |...|  ||         .||..:::
  Fly   335 ------FRTHAANNNLLNLPLPPAPPMSHHYH---HDALH--HL---------GPPNPATQ---- 375

  Fly   559 AAAAAVAAMSTPPNP 573
            ...||:|.|..||.|
  Fly   376 MGMAAMAHMLAPPPP 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ham	NP_724130.4	PR-SET_ZFPM	131..253	CDD:380978
		C2H2 Zn finger	341..363	CDD:275368	5/21 (24%)
		C2H2 Zn finger	371..392	CDD:275368	7/20 (35%)
		SFP1	<391..479	CDD:227516	30/115 (26%)
		C2H2 Zn finger	400..421	CDD:275368	9/20 (45%)
		SUF4-like	403..>445	CDD:411020	16/41 (39%)
		C2H2 Zn finger	403..421	CDD:411020	7/17 (41%)
		C2H2 Zn finger	429..449	CDD:275368	7/19 (37%)
		C2H2 Zn finger	457..477	CDD:275368	7/20 (35%)
		C2H2 Zn finger	486..504	CDD:275368	7/17 (41%)
		PTZ00121	<641..>728	CDD:173412
		COG5048	935..>1028	CDD:227381
		zf-C2H2	935..957	CDD:395048
		C2H2 Zn finger	937..957	CDD:275368
		zf-H2C2_2	949..973	CDD:404364
		C2H2 Zn finger	965..986	CDD:275368
		C2H2 Zn finger	994..1014	CDD:275368
CG17328	NP_609786.2	zf-AD	8..80	CDD:214871
		COG5048	146..>211	CDD:227381	18/64 (28%)
		C2H2 Zn finger	149..169	CDD:275368	5/21 (24%)
		C2H2 Zn finger	177..197	CDD:275368	7/20 (35%)
		zf-H2C2_2	189..213	CDD:404364	9/24 (38%)
		C2H2 Zn finger	205..225	CDD:275368	9/20 (45%)
		C2H2 Zn finger	233..253	CDD:275368	7/19 (37%)
		zf-H2C2_2	245..270	CDD:404364	9/24 (38%)
		C2H2 Zn finger	261..282	CDD:275368	7/20 (35%)
		C2H2 Zn finger	318..338	CDD:275368	8/30 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24393
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100