DRSC/TRiP Functional Genomics Resources

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Protein Alignment ham and Klf11

DIOPT Version :9

Sequence 1:NP_724130.4 Gene:ham / 35135 FlyBaseID:FBgn0045852 Length:1108 Species:Drosophila melanogaster
Sequence 2:NP_848134.1 Gene:Klf11 / 194655 MGIID:2653368 Length:502 Species:Mus musculus


Alignment Length:605 Identity:136/605 - (22%)
Similarity:190/605 - (31%) Gaps:194/605 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   508 STGPGPYRNQHV----------NRHHQHPHQHPLPHQPHLAATATSTC-----------PAPPRE 551
            |||||..|...:          .||........:..|..:.|.....|           |..|..
Mouse     6 STGPGDGRAADIMDICESILERKRHDSERSTCSVLEQTDIEAVEALVCMSSWGQRSQMRPLTPVS 70

  Fly   552 SSESSSSAAAAAVAAMSTPPNPFLMFRT---APSFFPGF--PPYGFPPFLPQN------------ 599
            .|...::|.....||...|.: |..|.|   .|...|..  |..|.|  :|..            
Mouse    71 DSGDVTTAVLMDTAAPDLPKD-FHSFSTLCITPPQSPELTEPSTGTP--VPSQVVNSKGCMVTAL 132

  Fly   600 PLHPTNIPMFFSK-NPMDLGCGG---PEITSPV-SAFDQKLPFGFLKGENSESQAYDKVTEKELV 659
            |..|...|...|| .|::...|.   ..:||.: ...:...|..|..|...|.:|.|        
Mouse   133 PPSPAGGPRTLSKREPLEPASGSSCRAVMTSVIRHTGESPAPTRFPTGPTQEQRASD-------- 189

  Fly   660 FKAEEKLKKEPLVQAFEGEEDESRSSLDIKGKLEDTRNDSKSEEQDDMKQEPERVSTPDQQQAED 724
                          :.||:|    ..||....|:|||                         ..:
Mouse   190 --------------SGEGQE----RLLDHLEALQDTR-------------------------LAN 211

  Fly   725 DRKSIDIMSTPPPADTPSGGDGPLDLSICRKRSAGSFFTAPAEDNLMLHRFMPRLHEFEAERGQP 789
            .....:::|..|                |..:|.|||.|...:                 :.|.|
Mouse   212 GLLVTNLVSCQP----------------CLHKSGGSFPTDKGQ-----------------QTGWP 243

  Fly   790 LKMRKS-HSSAESSTSQKSHKGSSPTP---TPTASPGLTPSPSPPTSAGGELSSTSEGGAVPTMA 850
            ..::.. ..:.||..|:|.      ||   .|.:||.:.....|.....|..|            
Mouse   244 AAVQTCLPKNPESDLSRKI------TPLISVPVSSPPVLCQMIPVAGQNGLFS------------ 290

  Fly   851 AAAFAADHSALASG---PTLPQTHPTFHPLLLEEIYRSGFPFLCQPGGRRGIEALLAGAASAAAP 912
              ||....:.|.:|   |.|||......|:.:......|...|..|.......|....:..|...
Mouse   291 --AFLKPPTQLPAGTIKPILPQAASMSQPVFMGPPVPQGTVMLVLPQNTFPQPAACPSSVMAIGN 353

  Fly   913 KRPLP----PVKFSAGS-----VVGLKTKDRYSCKF--CGKVFPRSANLTRHLRTHTGEQPYPCK 966
            .:.||    || |.|.|     .|....:..|.|.|  |.|.:.:|::|..||||||||:|:.|.
Mouse   354 TKLLPLAPAPV-FLASSQNCAPQVDFSRRRNYVCNFPGCRKTYFKSSHLKAHLRTHTGEKPFTCS 417

  Fly   967 Y--CDRAFSISSNLQRHVRNIHNKERPFRCELCDRSFGQQTNLDRHVKKH--------------- 1014
            :  ||:.|:.|..|.|| |..|..|:.|.|.:|||.|.:..:|.:|.::|               
Mouse   418 WDGCDKKFARSDELSRH-RRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMTTKKIPGWQAEVGK 481

  Fly  1015 -------ESEGNNFRDSPSS 1027
                   ||.|:.....|:|
Mouse   482 LNRITLAESPGSILEPLPAS 501

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hamNP_724130.4 PR-SET_ZFPM 131..253 CDD:380978
C2H2 Zn finger 341..363 CDD:275368
C2H2 Zn finger 371..392 CDD:275368
SFP1 <391..479 CDD:227516
C2H2 Zn finger 400..421 CDD:275368
SUF4-like 403..>445 CDD:411020
C2H2 Zn finger 403..421 CDD:411020
C2H2 Zn finger 429..449 CDD:275368
C2H2 Zn finger 457..477 CDD:275368
C2H2 Zn finger 486..504 CDD:275368
PTZ00121 <641..>728 CDD:173412 13/86 (15%)
COG5048 935..>1028 CDD:227381 41/119 (34%)
zf-C2H2 935..957 CDD:395048 10/23 (43%)
C2H2 Zn finger 937..957 CDD:275368 9/21 (43%)
zf-H2C2_2 949..973 CDD:404364 13/25 (52%)
C2H2 Zn finger 965..986 CDD:275368 9/22 (41%)
C2H2 Zn finger 994..1014 CDD:275368 7/19 (37%)
Klf11NP_848134.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 133..156 7/22 (32%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 169..194 7/46 (15%)
COG5048 382..>439 CDD:227381 25/57 (44%)
zf-C2H2 384..408 CDD:278523 10/23 (43%)
C2H2 Zn finger 389..408 CDD:275368 7/18 (39%)
zf-H2C2_2 400..427 CDD:290200 14/26 (54%)
C2H2 Zn finger 416..438 CDD:275368 9/22 (41%)
zf-H2C2_2 430..453 CDD:290200 11/23 (48%)
zf-C2H2 444..466 CDD:278523 8/21 (38%)
C2H2 Zn finger 446..466 CDD:275368 7/19 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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