Protein Alignment ham and ZNF211

DIOPT Version :9

• Sequence 1: NP_724130.4
• Gene: ham / 35135
• FlyBaseID: FBgn0045852
• Length: 1108
• Species: Drosophila melanogaster
• Sequence 2: NP_001252526.1
• Gene: ZNF211 / 10520
• HGNCID: 13003
• Length: 629
• Species: Homo sapiens
• Alignment Length: 818
• Identity: 146/818 - (17%)
• Similarity: 220/818 - (26%)
• Gaps: 420/818 - (51%)

  Fly   222 QSYINAGYLWYETNRYVNAGSEMVVD-------------GRPKSPVQLNEDFMNGGKVLAAAAAA 273
            |.||:|....::......|.....||             .:|.:..::.:||:...:.|..
Human   208 QFYISANLQQHQRQHITEAPFRSYVDTASFTQSCIVHVSEKPFTCREIRKDFLANMRFLHQ---- 268

  Fly   274 AAAVVAASSSGAKSGGGGSSAPSDDRSDRDNGSLYSGDEFSKDKKNSSLIREGDIDFTDDENGFD 338
                 .|:.:|.|.......|.          :.|||.......|
Human   269 -----DATQTGEKPNNSNKCAV----------AFYSGKSHHNWGK-------------------- 298

  Fly   339 IRCEVCDKVYPDLDLL--DDHLIGAHHFKQDEFPCKQCALRFCHRPLLIKHEAISHNNIRKYSCE 401
                 |.|.:..:|.|  |..::    .::..|.|.:|......|..||:|:.: |:..|.|.|.
Human   299 -----CSKAFSHIDTLVQDQRIL----TREGLFECSKCGKACTRRCNLIQHQKV-HSEERPYECN 353

  Fly   402 NCSKVFCDPSNLQRHIRAYHVGARCHPCPECGKTFGTSSGLKQHQHIHSSVKPFACEVCSKAYTQ 466
            .|.|.|...|:...|.|. |.|.|.:.||||||:|.....|..|:.:|:..:|:.|..|.|:::|
Human   354 ECGKFFTYYSSFIIHQRV-HTGERPYACPECGKSFSQIYSLNSHRKVHTGERPYECGECGKSFSQ 417

  Fly   467 FSNLCRHKRMHATCRMQIKCDKCNQSFSTLTSLTKHKKFCDSTGPGPYRNQHVNRHHQHPHQHPL 531
            .|||.:|:|:| |.....:|.:|.:|||...||.                     :||..|....
Human   418 RSNLMQHRRVH-TGERPYECSECGKSFSQNFSLI---------------------YHQRVHTGER 460

  Fly   532 PHQPHLAATATSTCPAPPRESSESSSSAAAAAVAAMSTPPNPFLMFRTAPSFFPGFPPYGFPPFL 596
            ||                 |.:|
Human   461 PH-----------------ECNE------------------------------------------ 466

  Fly   597 PQNPLHPTNIPMFFSKNPMDLGCGGPEITSPVSAFDQKLPFGFLKGENSESQAYDKVTEKELVFK 661
                                  ||
Human   467 ----------------------CG----------------------------------------- 468

  Fly   662 AEEKLKKEPLVQAFEGEEDESRSSLDIKGKLEDTRNDSKSEEQDDMKQEPERVSTPDQQQAEDDR 726
                       ::|      ||||
Human   469 -----------KSF------SRSS----------------------------------------- 475

  Fly   727 KSIDIMSTPPPADTPSGGDGPLDLSICRKRSAGSFFTAPAEDNLMLHRFMPRLHEFEAERGQPLK 791
                                                      :|:.||   |||..|    :|.:
Human   476 ------------------------------------------SLIHHR---RLHTGE----RPYE 491

  Fly   792 MRKSHSSAESSTSQKSHKGSSPTPTPTASPGLTPSPSPPTSAGGELSSTSEGGAVPTMAAAAFAA 856
            ..|...|.:.|:|..||:
Human   492 CSKCGKSFKQSSSFSSHR----------------------------------------------- 509

  Fly   857 DHSALASGPTLPQTHPTFHPLLLEEIYRSGFPFLCQPGGRRGIEALLAGAASAAAPKRPLPPVKF 921
                                    :::....|::|...|:                       .|
Human   510 ------------------------KVHTGERPYVCGECGK-----------------------SF 527

  Fly   922 SAGSVVGLKTKDR-------YSCKFCGKVFPRSANLTRHLRTHTGEQPYPCKYCDRAFSISSNLQ 979
            |..|  .||...|       ..|..|.|.|...:||.:|||.||||:||.|..|.::||.||:|.
Human   528 SHSS--NLKNHQRVHTGERPVECSECSKSFSCKSNLIKHLRVHTGERPYECSECGKSFSQSSSLI 590

  Fly   980 RHVRNIHNKERPFRCELCDRSFGQQTNLDRHVKKHESE 1017
            :| |.:|..:||::|..|.:|||.::.|.:|.:.|..|
Human   591 QH-RRVHTGKRPYQCSQCGKSFGCKSVLIQHQRVHIGE 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ham	NP_724130.4	PR-SET_ZFPM	131..253	CDD:380978	8/43 (19%)
		C2H2 Zn finger	341..363	CDD:275368	5/23 (22%)
		C2H2 Zn finger	371..392	CDD:275368	6/20 (30%)
		SFP1	<391..479	CDD:227516	34/87 (39%)
		C2H2 Zn finger	400..421	CDD:275368	7/20 (35%)
		SUF4-like	403..>445	CDD:411020	17/41 (41%)
		C2H2 Zn finger	403..421	CDD:411020	6/17 (35%)
		C2H2 Zn finger	429..449	CDD:275368	9/19 (47%)
		C2H2 Zn finger	457..477	CDD:275368	9/19 (47%)
		C2H2 Zn finger	486..504	CDD:275368	7/17 (41%)
		PTZ00121	<641..>728	CDD:173412	5/86 (6%)
		COG5048	935..>1028	CDD:227381	36/83 (43%)
		zf-C2H2	935..957	CDD:395048	9/21 (43%)
		C2H2 Zn finger	937..957	CDD:275368	9/19 (47%)
		zf-H2C2_2	949..973	CDD:404364	13/23 (57%)
		C2H2 Zn finger	965..986	CDD:275368	9/20 (45%)
		C2H2 Zn finger	994..1014	CDD:275368	7/19 (37%)
ZNF211	NP_001252526.1	KRAB	46..106	CDD:214630
		KRAB	46..85	CDD:279668
		COG5048	244..615	CDD:227381	135/768 (18%)
		C2H2 Zn finger	299..316	CDD:275368	5/16 (31%)
		C2H2 Zn finger	324..344	CDD:275368	6/20 (30%)
		zf-H2C2_2	336..361	CDD:290200	10/25 (40%)
		C2H2 Zn finger	352..372	CDD:275368	7/20 (35%)
		zf-H2C2_2	368..389	CDD:290200	12/21 (57%)
		C2H2 Zn finger	380..400	CDD:275368	9/19 (47%)
		zf-H2C2_2	392..417	CDD:290200	7/24 (29%)
		C2H2 Zn finger	408..428	CDD:275368	9/19 (47%)
		zf-H2C2_2	420..445	CDD:290200	10/25 (40%)
		C2H2 Zn finger	436..456	CDD:275368	9/40 (23%)
		zf-H2C2_2	448..473	CDD:290200	12/184 (7%)
		C2H2 Zn finger	464..484	CDD:275368	12/227 (5%)
		zf-C2H2	518..540	CDD:278523	8/46 (17%)
		C2H2 Zn finger	520..540	CDD:275368	8/44 (18%)
		zf-H2C2_2	532..557	CDD:290200	7/24 (29%)
		C2H2 Zn finger	548..568	CDD:275368	9/19 (47%)
		zf-H2C2_2	560..585	CDD:290200	14/24 (58%)
		C2H2 Zn finger	576..596	CDD:275368	9/20 (45%)
		zf-H2C2_2	588..611	CDD:290200	8/23 (35%)
		C2H2 Zn finger	604..624	CDD:275368	7/19 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000