DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG10348 and KLF11

DIOPT Version :9

Sequence 1:NP_001286059.1 Gene:CG10348 / 35132 FlyBaseID:FBgn0032707 Length:540 Species:Drosophila melanogaster
Sequence 2:NP_003588.1 Gene:KLF11 / 8462 HGNCID:11811 Length:512 Species:Homo sapiens


Alignment Length:411 Identity:98/411 - (23%)
Similarity:133/411 - (32%) Gaps:132/411 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    39 LASSASVAATSSSS------------TSPTTTSATTTGRLQHQHSHQQHQTLNHHAKGKRRSSFD 91
            |.|||.||...|..            :||.....|:..|               |......:.|.
Human   139 LQSSAVVARALSGGAERGLLGLEPVPSSPCRAKGTSVIR---------------HTGESPAACFP 188

  Fly    92 --QPLDLRLAHKRKTDLVDQGPMEDENSNLIMFASELAVAQQKEKELNNNHIAASLADLGFDMSR 154
              |..|.||:..|          |.|...|..|           :.|.:.|:..||........:
Human   189 TIQTPDCRLSDSR----------EGEEQLLGHF-----------ETLQDTHLTDSLLSTNLVSCQ 232

  Fly   155 KMLRALREGGA----GGGGGGGGGGGGGGGPPN------------------APPL---------- 187
            ..|.  :.||.    .|...|..|......|.|                  |||:          
Human   233 PCLH--KSGGLLLTDKGQQAGWPGAVQTCSPKNYENDLPRKTTPLISVSVPAPPVLCQMIPVTGQ 295

  Fly   188 ---------TPPQCSIPAVHPTLLEAMTKNLPLQYRNVFAGVLPGKVNSPAASSSPTGADFPFRH 243
                     .|||.|:..|.|.|.:|.....|     ||.|  |...........|.||      
Human   296 SSMLPAFLKPPPQLSVGTVRPILAQAAPAPQP-----VFVG--PAVPQGAVMLVLPQGA------ 347

  Fly   244 PLKKCELTWPPPTEQLQLELPHPNPKLSPVLPHPQLQDYQTRRKNKARTAATGGNATPNLPQRNK 308
                    .|||.......:...|.||.|:.|.|..             ..:..|..|.:....:
Human   348 --------LPPPAPCAANVMAAGNTKLLPLAPAPVF-------------ITSSQNCVPQVDFSRR 391

  Fly   309 DRYTCKF--CGKVFPRSANLTRHLRTHTGEQPYKCKY--CERSFSISSNLQRHVRNIHNKERPFK 369
            ..|.|.|  |.|.:.:|::|..||||||||:|:.|.:  |::.|:.|..|.|| |..|..|:.|.
Human   392 RNYVCSFPGCRKTYFKSSHLKAHLRTHTGEKPFNCSWDGCDKKFARSDELSRH-RRTHTGEKKFV 455

  Fly   370 CEICERCFGQQTNLDRHLKKH 390
            |.:|:|.|.:..:|.:|.::|
Human   456 CPVCDRRFMRSDHLTKHARRH 476

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10348NP_001286059.1 COG5048 300..>363 CDD:227381 25/66 (38%)
zf-C2H2 311..333 CDD:278523 10/23 (43%)
C2H2 Zn finger 313..333 CDD:275368 9/21 (43%)
zf-H2C2_2 325..349 CDD:290200 12/25 (48%)
C2H2 Zn finger 341..362 CDD:275368 8/22 (36%)
zf-H2C2_2 353..377 CDD:290200 10/23 (43%)
zf-C2H2 368..390 CDD:278523 7/21 (33%)
C2H2 Zn finger 370..390 CDD:275368 6/19 (32%)
KLF11NP_003588.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 109..128
COG5048 393..>449 CDD:227381 24/56 (43%)
zf-C2H2 394..418 CDD:278523 10/23 (43%)
C2H2 Zn finger 399..418 CDD:275368 7/18 (39%)
zf-H2C2_2 410..437 CDD:290200 13/26 (50%)
C2H2 Zn finger 426..448 CDD:275368 8/22 (36%)
zf-H2C2_2 440..463 CDD:290200 10/23 (43%)
zf-C2H2 454..476 CDD:278523 7/21 (33%)
C2H2 Zn finger 456..476 CDD:275368 6/19 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.