DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and Klf5

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_445846.3	Gene:	Klf5 / 84410	RGDID:	621446	Length:	443	Species:	Rattus norvegicus

Alignment Length:	218	Identity:	69/218 - (31%)
Similarity:	104/218 - (47%)	Gaps:	32/218 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   183 NAPPLTPPQCSIPAVHPTLLEAMTKNLPLQYRNVFAGVLPGKVNSPAASSSPTGADFPFRHPLKK 247
            |:.|...||.|:.....  :...|..:|.|:....|...|     |:..||..|:  |.|.....
  Rat   250 NSHPSAVPQTSMKQFQG--MPPCTYTMPSQFLPQQATYFP-----PSPPSSEPGS--PDRQAEML 305

  Fly   248 CELTWPPPT--EQLQLELPHPNPKLSPVLP--HPQLQDYQTRRKNKARTAATGGNATPNLPQRNK 308
            ..|| |||:  ..:..:|...||.|...||  .|.:|..:..|:           :.|:|.:|.
  Rat   306 QNLT-PPPSYAATIASKLAIHNPNLPATLPVNSPNIQPVRYNRR-----------SNPDLEKRR- 357

  Fly   309 DRYTCKF--CGKVFPRSANLTRHLRTHTGEQPYKCKY--CERSFSISSNLQRHVRNIHNKERPFK 369
             .:.|.:  |.||:.:|::|..||||||||:||||.:  |:..|:.|..|.||.|. |...:||:
  Rat   358 -IHFCDYDGCTKVYTKSSHLKAHLRTHTGEKPYKCTWEGCDWRFARSDELTRHYRK-HTGAKPFQ 420

  Fly   370 CEICERCFGQQTNLDRHLKKHES 392
            |.:|.|.|.:..:|..|:|:|::
  Rat   421 CVVCNRSFSRSDHLALHMKRHQN 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	28/66 (42%)
		zf-C2H2	311..333	CDD:278523	9/23 (39%)
		C2H2 Zn finger	313..333	CDD:275368	9/21 (43%)
		zf-H2C2_2	325..349	CDD:290200	14/25 (56%)
		C2H2 Zn finger	341..362	CDD:275368	8/22 (36%)
		zf-H2C2_2	353..377	CDD:290200	10/23 (43%)
		zf-C2H2	368..390	CDD:278523	8/21 (38%)
		C2H2 Zn finger	370..390	CDD:275368	7/19 (37%)
Klf5	NP_445846.3	KLF5_N	3..356	CDD:410335	32/126 (25%)
		COG5048	345..>419	CDD:227381	30/87 (34%)
		C2H2 Zn finger	361..383	CDD:275368	9/21 (43%)
		C2H2 Zn finger	391..413	CDD:275368	8/22 (36%)
		zf-H2C2_2	405..430	CDD:404364	11/25 (44%)
		zf-C2H2	419..441	CDD:395048	8/21 (38%)
		C2H2 Zn finger	421..441	CDD:275368	7/19 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910