DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG10348 and GFI1B

DIOPT Version :9

Sequence 1:NP_001286059.1 Gene:CG10348 / 35132 FlyBaseID:FBgn0032707 Length:540 Species:Drosophila melanogaster
Sequence 2:NP_001358837.1 Gene:GFI1B / 8328 HGNCID:4238 Length:352 Species:Homo sapiens


Alignment Length:233 Identity:58/233 - (24%)
Similarity:97/233 - (41%) Gaps:23/233 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly   178 GGGP-PNAPPLTPPQCSIPAVHPTLLEAMTKNLPLQYRNVFAGVLPGKVNSPAASSSPTGADFPF 241
            |..| .::||...|..|...:..|...:. :..|...::.|.........||...|:....||..
Human    91 GDSPLSDSPPFYKPSFSWDTLATTYGHSY-RQAPSTMQSAFLEHSVSLYGSPLVPSTEPALDFSL 154

  Fly   242 RHP-------LKKCELTWPPPTEQLQLELPHPNPKLSP--------VLPHPQLQDYQTRRKNKAR 291
            |:.       ..||...:..| ..|::.:...:....|        ...|....:..|...::..
Human   155 RYSPGMDAYHCVKCNKVFSTP-HGLEVHVRRSHSGTRPFACDICGKTFGHAVSLEQHTHVHSQGI 218

  Fly   292 TAATGGNATPNLP----QRNKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISS 352
            .|.:.....|:.|    .|.:..:.|:.|||.|.||:.|:.||..|:..:||.|::|.:.|...|
Human   219 PAGSSPEPAPDPPGPHFLRQERSFECRMCGKAFKRSSTLSTHLLIHSDTRPYPCQFCGKRFHQKS 283

  Fly   353 NLQRHVRNIHNKERPFKCEICERCFGQQTNLDRHLKKH 390
            ::::|. .||..|:|.||::|.:.|.|.:||..|.:||
Human   284 DMKKHT-YIHTGEKPHKCQVCGKAFSQSSNLITHSRKH 320

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10348NP_001286059.1 COG5048 300..>363 CDD:227381 22/66 (33%)
zf-C2H2 311..333 CDD:278523 10/21 (48%)
C2H2 Zn finger 313..333 CDD:275368 10/19 (53%)
zf-H2C2_2 325..349 CDD:290200 8/23 (35%)
C2H2 Zn finger 341..362 CDD:275368 5/20 (25%)
zf-H2C2_2 353..377 CDD:290200 8/23 (35%)
zf-C2H2 368..390 CDD:278523 8/21 (38%)
C2H2 Zn finger 370..390 CDD:275368 7/19 (37%)
GFI1BNP_001358837.1 C2H2 Zn finger 165..186 CDD:275368 4/21 (19%)
C2H2 Zn finger 194..214 CDD:275368 2/19 (11%)
C2H2 Zn finger 244..264 CDD:275368 10/19 (53%)
COG5048 252..>329 CDD:227381 27/70 (39%)
C2H2 Zn finger 272..292 CDD:275368 5/20 (25%)
zf-H2C2_2 284..309 CDD:372612 9/25 (36%)
C2H2 Zn finger 300..320 CDD:275368 7/19 (37%)
C2H2 Zn finger 328..345 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.