DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and klf12a

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_021331523.1	Gene:	klf12a / 798629	ZFINID:	ZDB-GENE-030131-9188	Length:	380	Species:	Danio rerio

Alignment Length:	395	Identity:	96/395 - (24%)
Similarity:	148/395 - (37%)	Gaps:	129/395 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 PYDLA-----SSASVAATSSSSTSPTTTSATTTGRLQHQHSHQQHQTLNHHAKGKRRSSFDQPLD 95
            |.||:     :|.|::|:||.|:||:::|::.....:...|          :|....||   |..
Zfish    68 PVDLSTNKARTSPSLSASSSLSSSPSSSSSSIRFCPRSPPS----------SKSLPSSS---PSS 119

  Fly    96 LRLAHKRKTDLVDQGPMEDENSNLIMFASELAVAQQKEKELNNNHIAASLADLGFDMSRKMLRAL 160
            |.:.....|.::...|.       :..:...:|.           :.:||..          |.|
Zfish   120 LSMPSSSSTSVITPVPR-------LKMSPSCSVP-----------VVSSLPS----------RGL 156

  Fly   161 REGGAGGGGGGGGGGGGGGGPPNAPPLTPPQCSIPA-VHPTLLEAMTKNLPLQYRNVFAGVLPGK 224
            |                |....:.|.|.|| ||.|. :||..:..:.:.:||.|        ||
Zfish   157 R----------------GQSFLHIPQLMPP-CSSPVHIHPRRVPVVVQPMPLVY--------PG- 195

  Fly   225 VNSPAASSSPTGADFPFRHPLKKCELTWPPPTE-QLQLELPH-------PNPKLSPV----LPHP 277
            |.|..:|                 .|..|...| ::..::.|       |...||..    ||:.
Zfish   196 VGSLGSS-----------------RLMMPLLEENRMHRKVMHRMADGLSPRRSLSDSEDDDLPNV 243

  Fly   278 QLQDYQTRRKNKARTAATGGNATPN--LP----------------QRNKDRYTCKF--CGKVFPR 322
            .|:..    .....||.|...|..:  ||                .:.:..:.|:|  |.||:.:
Zfish   244 TLESV----NETGSTALTIARAVQDSLLPFSIESLRRPRPSESPDSKRRRIHRCEFEGCNKVYTK 304

  Fly   323 SANLTRHLRTHTGEQPYKCKY--CERSFSISSNLQRHVRNIHNKERPFKCEICERCFGQQTNLDR 385
            |::|..|.||||||:||||.:  |...|:.|..|.||.|. |...:||||..|:|.|.:..:|..
Zfish   305 SSHLKAHRRTHTGEKPYKCTWDNCTWKFARSDELTRHYRK-HTGVKPFKCSDCDRSFSRSDHLAL 368

  Fly   386 HLKKH 390
            |.::|
Zfish   369 HRRRH 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	27/84 (32%)
		zf-C2H2	311..333	CDD:278523	9/23 (39%)
		C2H2 Zn finger	313..333	CDD:275368	9/21 (43%)
		zf-H2C2_2	325..349	CDD:290200	13/25 (52%)
		C2H2 Zn finger	341..362	CDD:275368	8/22 (36%)
		zf-H2C2_2	353..377	CDD:290200	11/23 (48%)
		zf-C2H2	368..390	CDD:278523	8/21 (38%)
		C2H2 Zn finger	370..390	CDD:275368	6/19 (32%)
klf12a	XP_021331523.1	SFP1	<217..370	CDD:227516	47/157 (30%)
		C2H2 Zn finger	296..315	CDD:275368	7/18 (39%)
		C2H2 Zn finger	323..345	CDD:275368	8/22 (36%)
		zf-H2C2_2	337..362	CDD:316026	12/25 (48%)
		C2H2 Zn finger	353..373	CDD:275368	6/19 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910