DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10348 and zgc:175107

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001107104.1	Gene:	zgc:175107 / 794317	ZFINID:	ZDB-GENE-080220-38	Length:	333	Species:	Danio rerio

Alignment Length:	167	Identity:	52/167 - (31%)
Similarity:	80/167 - (47%)	Gaps:	19/167 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   256 TEQLQLE----LPHPNPKLSPVLPHPQLQDYQT-----RRKNKARTAATGGNATP-------NLP 304
            :|.|::|    :.|.:......|..|:::..:|     |.:...|.:|.|..:|.       ..|
Zfish     8 SEDLKIEHTFTVKHEDRDKQTDLTAPKVERQETNELEERNQYDKRDSAIGEKSTHTQDASLLKRP 72

  Fly   305 Q--RNKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKERP 367
            |  .:...|.|..|.|.|....||..|.||||||:|:.|:.|.:|||...||:.|:| :|..|:|
Zfish    73 QSAESSGYYICGECNKSFGLKQNLEVHKRTHTGEKPFSCQQCGKSFSQKQNLKVHMR-VHTGEKP 136

  Fly   368 FKCEICERCFGQQTNLDRHLKKHESDAVSLSALSGVS 404
            |.|..|.:.|..:.||..|::.|..::..:..|.|.|
Zfish   137 FSCPFCGQNFTHKGNLKTHVRNHTGESAFICNLCGKS 173

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	27/71 (38%)
		zf-C2H2	311..333	CDD:278523	9/21 (43%)
		C2H2 Zn finger	313..333	CDD:275368	8/19 (42%)
		zf-H2C2_2	325..349	CDD:290200	13/23 (57%)
		C2H2 Zn finger	341..362	CDD:275368	9/20 (45%)
		zf-H2C2_2	353..377	CDD:290200	10/23 (43%)
		zf-C2H2	368..390	CDD:278523	7/21 (33%)
		C2H2 Zn finger	370..390	CDD:275368	6/19 (32%)
zgc:175107	NP_001107104.1	C2H2 Zn finger	83..103	CDD:275368	8/19 (42%)
		zf-H2C2_2	95..120	CDD:290200	14/24 (58%)
		COG5048	<107..286	CDD:227381	24/68 (35%)
		C2H2 Zn finger	111..131	CDD:275368	9/20 (45%)
		zf-H2C2_2	123..148	CDD:290200	11/25 (44%)
		C2H2 Zn finger	139..159	CDD:275368	6/19 (32%)
		zf-C2H2	165..187	CDD:278523	3/9 (33%)
		C2H2 Zn finger	167..187	CDD:275368	3/7 (43%)
		C2H2 Zn finger	195..215	CDD:275368
		C2H2 Zn finger	223..243	CDD:275368
		C2H2 Zn finger	251..271	CDD:275368
		zf-H2C2_2	264..287	CDD:290200
		C2H2 Zn finger	279..299	CDD:275368
		zf-H2C2_2	291..316	CDD:290200
		C2H2 Zn finger	307..324	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910