DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10348 and ZNF143

DIOPT Version :9

Sequence 1:NP_001286059.1 Gene:CG10348 / 35132 FlyBaseID:FBgn0032707 Length:540 Species:Drosophila melanogaster
Sequence 2:XP_005253178.1 Gene:ZNF143 / 7702 HGNCID:12928 Length:653 Species:Homo sapiens


Alignment Length:288 Identity:67/288 - (23%)
Similarity:93/288 - (32%) Gaps:107/288 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly   309 DR-YTCKF--CGKVFPRSANLTRHLRTHTGEQPYKCK--YCERSFSISSNLQRHVRNIHNKERPF 368
            || |.|:.  |||.|.....|..|:||||||:||:|.  .|.:||..|.:||:|:|. |..||||
Human   279 DRPYQCEHAGCGKAFATGYGLKSHVRTHTGEKPYRCSEDNCTKSFKTSGDLQKHIRT-HTGERPF 342

  Fly   369 KCEI--------------------------------CERCFGQQTNLDRHLKKHESDAVSLSALS 401
            ||..                                |.|.|...||...|::.|..:...:..:.
Human   343 KCPFEGCGRSFTTSNIRKVHVRTHTGERPYYCTEPGCGRAFASATNYKNHVRIHTGEKPYVCTVP 407

  Fly   402 GVSERM----------------------HC------------IRRFCENPTE------ESYFE-- 424
            |..:|.                      ||            .:|...|.||      |::||  
Human   408 GCDKRFTEYSSLYKHHVVHTHSKPYNCNHCGKTYKQISTLAMHKRTAHNDTEPIEEEQEAFFEPP 472

  Fly   425 ----------------------EIRSFMGKVTQQQQQQQQQQQHDQQQQQHQSTATSASSSCSSS 467
                                  ::.|.......|....||.....|...||.:.:.:...:..::
Human   473 PGQGEDVLKGSQITYVTGVEGDDVVSTQVATVTQSGLSQQVTLISQDGTQHVNISQADMQAIGNT 537

  Fly   468 RDTPTSSHEEADHAPATSTADTAAPSSS 495
            ....|.     |..|.|..|..|..||:
Human   538 ITMVTQ-----DGTPITVPAHDAVISSA 560

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10348NP_001286059.1 COG5048 300..>363 CDD:227381 27/58 (47%)
zf-C2H2 311..333 CDD:278523 9/23 (39%)
C2H2 Zn finger 313..333 CDD:275368 8/21 (38%)
zf-H2C2_2 325..349 CDD:290200 13/25 (52%)
C2H2 Zn finger 341..362 CDD:275368 9/22 (41%)
zf-H2C2_2 353..377 CDD:290200 13/55 (24%)
zf-C2H2 368..390 CDD:278523 9/53 (17%)
C2H2 Zn finger 370..390 CDD:275368 7/51 (14%)
ZNF143XP_005253178.1 Trp-synth-beta_II <97..207 CDD:294246
C2H2 Zn finger 254..276 CDD:275368
zf-H2C2_2 268..295 CDD:290200 8/15 (53%)
COG5048 279..>337 CDD:227381 27/58 (47%)
C2H2 Zn finger 284..306 CDD:275368 8/21 (38%)
zf-H2C2_2 299..325 CDD:290200 14/25 (56%)
zf-C2H2_8 314..429 CDD:292531 25/115 (22%)
C2H2 Zn finger 314..336 CDD:275368 9/22 (41%)
zf-H2C2_2 328..355 CDD:290200 11/27 (41%)
C2H2 Zn finger 344..366 CDD:275368 1/21 (5%)
zf-H2C2_2 360..385 CDD:290200 3/24 (13%)
C2H2 Zn finger 374..396 CDD:275368 6/21 (29%)
zf-H2C2_2 388..414 CDD:290200 5/25 (20%)
C2H2 Zn finger 404..426 CDD:275368 2/21 (10%)
C2H2 Zn finger 434..453 CDD:275368 2/18 (11%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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