DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10348 and ZKSCAN1

DIOPT Version :9

Sequence 1:NP_001286059.1 Gene:CG10348 / 35132 FlyBaseID:FBgn0032707 Length:540 Species:Drosophila melanogaster
Sequence 2:NP_001333510.1 Gene:ZKSCAN1 / 7586 HGNCID:13101 Length:563 Species:Homo sapiens


Alignment Length:259 Identity:69/259 - (26%)
Similarity:110/259 - (42%) Gaps:49/259 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   255 PTEQLQLELPHPNPKLSPVLPHPQLQDYQT-------RRKNK--ARTAATGGN-ATPNLPQRNKD 309
            |.|:.:.|.....|.:.        :|.:|       |.|.|  .|:.:...| .||........
Human   319 PEEKTRKEKRDSGPAIG--------KDKKTITGERGPREKGKGLGRSFSLSSNFTTPEEVPTGTK 375

  Fly   310 RYTCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKERPFKCEICE 374
            .:.|..|||.|.||::|.||...||||:||:|..|.::||::|||..|.| ||..|:|.:|..|.
Human   376 SHRCDECGKCFTRSSSLIRHKIIHTGEKPYECSECGKAFSLNSNLVLHQR-IHTGEKPHECNECG 439

  Fly   375 RCFGQQTNLDRHLKKHESD----------AVSLSALSGVSERMHCIRRFCENPTEESYFEEIRSF 429
            :.|...:||..|.:.|..:          |.|.|:.....:|:|         |.|..:|  .|.
Human   440 KAFSHSSNLILHQRIHSGEKPYECNECGKAFSQSSDLTKHQRIH---------TGEKPYE--CSE 493

  Fly   430 MGKVTQQQQQQQQQQQHDQQQQQHQSTATSASSSCSSSRDTPTSSH------EEADHAPATSTA 487
            .||...:.......::...:::.::.|....:.:.||   |.|..|      ..::::||:..|
Human   494 CGKAFNRNSYLILHRRIHTREKPYKCTKCGKAFTRSS---TLTLHHRIHARERASEYSPASLDA 554

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10348NP_001286059.1 COG5048 300..>363 CDD:227381 28/62 (45%)
zf-C2H2 311..333 CDD:278523 10/21 (48%)
C2H2 Zn finger 313..333 CDD:275368 10/19 (53%)
zf-H2C2_2 325..349 CDD:290200 11/23 (48%)
C2H2 Zn finger 341..362 CDD:275368 9/20 (45%)
zf-H2C2_2 353..377 CDD:290200 10/23 (43%)
zf-C2H2 368..390 CDD:278523 6/21 (29%)
C2H2 Zn finger 370..390 CDD:275368 6/19 (32%)
ZKSCAN1NP_001333510.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..51
SCAN 52..162 CDD:128708
KRAB_A-box 227..262 CDD:143639
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 257..373 13/61 (21%)
C2H2 Zn finger 355..371 CDD:275368 4/15 (27%)
COG5048 <356..537 CDD:227381 56/195 (29%)
C2H2 Zn finger 379..399 CDD:275368 10/19 (53%)
C2H2 Zn finger 407..427 CDD:275368 9/20 (45%)
C2H2 Zn finger 435..455 CDD:275368 6/19 (32%)
C2H2 Zn finger 463..483 CDD:275368 4/19 (21%)
C2H2 Zn finger 491..511 CDD:275368 3/19 (16%)
C2H2 Zn finger 519..539 CDD:275368 6/22 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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