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Protein Alignment CG10348 and ZNF18

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001290210.1	Gene:	ZNF18 / 7566	HGNCID:	12969	Length:	549	Species:	Homo sapiens

Alignment Length:	492	Identity:	114/492 - (23%)
Similarity:	170/492 - (34%)	Gaps:	165/492 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 PSPKQGCVYPALGLIPTSY----ISHVPYDLASSASVAATSSSSTSPTTTSATTTGRLQHQ---- 69
            ||.:.|.|.|.|.::|...    .|..|.:|.|  .:....|.:.:....:|:...||:.:
Human   147 PSCQVGEVEPHLEVVPQELGLENSSSGPGELLS--HIVKEESDTEAELALAASQPARLEERLIRD 209

  Fly    70 ----------HSHQQHQTLNHHAKGKRRSSFDQPLDLRL------------AHKRKTDLVDQGPM 112
                      ...:|.:.|:...|       :|..||.|            :|. |:||.:....
Human   210 QDLGASLLPAAPQEQWRQLDSTQK-------EQYWDLMLETYGKMVSGAGISHP-KSDLTNSIEF 266

  Fly   113 EDENSNLIMFASE-------LAVAQQKEKE-LN-NNH-----IAASLADLGFDMSRKMLRAL--- 160
            .:|.:.:.:..:|       :...|:.:|| || .||     :.||....|...|:..||..
Human   267 GEELAGIYLHVNEKIPRPTCIGDRQENDKENLNLENHRDQELLHASCQASGEVPSQASLRGFFTE 331

  Fly   161 REGGAGGGGGGGGGGGGGGGPPNAPPLTPPQCSIPAVHPTLLEAMTKNLPLQYRNVFAGVLPGKV 225
            .|.|..|.|                                     :|||...:|:
Human   332 DEPGCFGEG-------------------------------------ENLPEALQNI--------- 350

  Fly   226 NSPAASSSPTGADFPFRHPLKKCELTWPPPTEQLQLELPHPNPKLSPVLPHPQLQDYQTR-RKNK 289
                 ....||                    |||..:......:|...||:|...:..|. .:.|
Human   351 -----QDEGTG--------------------EQLSPQERISEKQLGQHLPNPHSGEMSTMWLEEK 390

  Fly   290 ARTAATGGNATP---NLP------------------QR---NKDRYTCKFCGKVFPRSANLTRHL 330
            ..|:..|....|   .||                  ||   .:..:.|..|.|.|.||::..:|.
Human   391 RETSQKGQPRAPMAQKLPTCRECGKTFYRNSQLIFHQRTHTGETYFQCTICKKAFLRSSDFVKHQ 455

  Fly   331 RTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKERPFKCEICERCFGQQTNLDRHLKKHESDAV 395
            ||||||:|.||.||.:.||..|.| ||...||..|:|:||.|||:.|.|::|.:||.:.|..:..
Human   456 RTHTGEKPCKCDYCGKGFSDFSGL-RHHEKIHTGEKPYKCPICEKSFIQRSNFNRHQRVHTGEKP 519

  Fly   396 SLSALSGVSERMHCIRRFCENPTEESYFEEIRSFMGK 432
            ...:        ||.:.|   ....|..:..||.:||
Human   520 YKCS--------HCGKSF---SWSSSLDKHQRSHLGK 545

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.