DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10348 and klf11

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_012818552.1	Gene:	klf11 / 733909	XenbaseID:	XB-GENE-956858	Length:	500	Species:	Xenopus tropicalis

Alignment Length:	257	Identity:	70/257 - (27%)
Similarity:	111/257 - (43%)	Gaps:	54/257 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   181 PPNAPPLTPPQCSIPAVHPTLLEAMTKNLPLQYRNVFAGVLPGKVNSPAASSSPTGAD-FPFRHP 244
            |..|..|.|  .|:|.....||..|   :|:..:   |||:...:..|:...|.|... .|...|
Frog   248 PKEANQLLP--ISVPVSSSPLLCQM---IPVTGQ---AGVISAFIKPPSQPISNTVKPILPQSSP 304

  Fly   245 LKKCELTWPPPTE-QLQLELPHP-----------------NPKLSPVLPHPQLQDYQTRRKNKAR 291
            :.:..|...|.:: .|.|.||..                 |.||.|:.|.|..
Frog   305 VSQPVLMGAPVSQGALMLVLPQAPIPQSPQQCPQTLVAVGNTKLLPLAPAPVF------------ 357

  Fly   292 TAATGGNATPNLPQRNKDRYTCKF--CGKVFPRSANLTRHLRTHTGEQPYKCKY--CERSFSISS 352
             .|:|.::.|.:....:..|.|.|  |.|.:.:|::|..||||||||:|:.|.:  |::.|:.|.
Frog   358 -IASGQSSPPQMDFSRRRNYVCNFSGCRKTYFKSSHLKAHLRTHTGEKPFSCNWEGCDKKFARSD 421

  Fly   353 NLQRHVRNIHNKERPFKCEICERCFGQQTNLDRHLKKH---------ESDAVSLSALSGVSE 405
            .|.|| |..|..|:.|.|.:|:|.|.:..:|.:|.::|         :::...|:.:||..:
Frog   422 ELSRH-RRTHTGEKKFACPVCDRRFMRSDHLTKHARRHMTTKKVPAWQAEVGKLNRISGTDK 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	25/66 (38%)
		zf-C2H2	311..333	CDD:278523	10/23 (43%)
		C2H2 Zn finger	313..333	CDD:275368	9/21 (43%)
		zf-H2C2_2	325..349	CDD:290200	12/25 (48%)
		C2H2 Zn finger	341..362	CDD:275368	8/22 (36%)
		zf-H2C2_2	353..377	CDD:290200	10/23 (43%)
		zf-C2H2	368..390	CDD:278523	7/21 (33%)
		C2H2 Zn finger	370..390	CDD:275368	6/19 (32%)
klf11	XP_012818552.1	PHA03247	<95..366	CDD:223021	32/138 (23%)
		COG5048	360..>431	CDD:227381	26/71 (37%)
		C2H2 Zn finger	381..400	CDD:275368	7/18 (39%)
		C2H2 Zn finger	408..430	CDD:275368	8/22 (36%)
		zf-H2C2_2	422..445	CDD:372612	10/23 (43%)
		zf-C2H2	436..458	CDD:333835	7/21 (33%)
		C2H2 Zn finger	438..458	CDD:275368	6/19 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910