DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and sp3

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_002934651.1	Gene:	sp3 / 733736	XenbaseID:	XB-GENE-977158	Length:	750	Species:	Xenopus tropicalis

Alignment Length:	440	Identity:	107/440 - (24%)
Similarity:	162/440 - (36%)	Gaps:	149/440 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 TSSSSTSPTTTSATTTGRLQHQHSHQQHQTLNHHAKGKRRSSFDQPLDLRLAHKRKTDL---VDQ 109
            |||||..|.|...  ||.||        |..|        |..|.|    ..|.:.:||   ..|
Frog   290 TSSSSQLPVTIDG--TGMLQ--------QNAN--------SLTDSP----SGHVQTSDLHGNYIQ 332

  Fly   110 GPMEDENSNLIMFASELAVAQ---QKEKELNNNHIAASLADLGFDMSRKMLRALREGGAGGGGGG 171
            ..|.||:.|:.:.||:..|.|   |..:..:...:..|:|       ::.::|::         |
Frog   333 TSMTDESQNIQVSASQTMVQQIHLQDSQPTSQAQLVQSIA-------QQAIQAVQ---------G 381

  Fly   172 GGGGGGGGGPPN-------------APPLTP----------------------PQCSIPAVHPTL 201
            |..|.......|             |..:||                      |..|...:..|.
Frog   382 GTQGLSSQALQNLQLQLNPGTFLIQAQTVTPSGQIAWQTFQVQGVQNLQNLQIPNSSAQQITLTP 446

  Fly   202 LEAMT------KNLPLQYRNVFAGVLPG----KVNSPAA----------SSSPTG---------- 236
            ::.:|      ...|:   ::.||.||.    .|||..|          |.|||.
Frog   447 VQTLTLGQVAGGGTPV---SLNAGQLPNLQTVTVNSVDAAGIHLHHGDNSDSPTEIETHQTRQHF 508

  Fly   237 -----ADFPFRHPLKKCELTWPPPTEQLQL---------ELPHPNPKLSPVLPHPQLQDYQTRRK 287
                 ::|..|  :|:.|    |..::.||         :|.|    |...:...:|.......|
Frog   509 SSLQLSNFGIR--IKEEE----PDPDEWQLAGDSTVNTNDLTH----LRVQVVDDELDQPNQEGK 563

  Fly   288 NKARTAAT------GGNATPNLPQRNKDRYTCKF--CGKVFPRSANLTRHLRTHTGEQPYKC--K 342
            ...|.|.|      |.....||.:  |.::.|..  ||||:.::::|..|||.|:||:|:.|  .
Frog   564 RLRRVACTCPNCKDGAGRGTNLGK--KKQHICHIPGCGKVYGKTSHLRAHLRWHSGERPFVCTWM 626

  Fly   343 YCERSFSISSNLQRHVRNIHNKERPFKCEICERCFGQQTNLDRHLKKHES 392
            :|.:.|:.|..|||| |..|..|:.|.|..|.:.|.:..:|.:|:|.|::
Frog   627 FCGKRFTRSDELQRH-RRTHTGEKKFVCPECSKRFMRSDHLAKHIKTHQN 675

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	25/66 (38%)
		zf-C2H2	311..333	CDD:278523	9/23 (39%)
		C2H2 Zn finger	313..333	CDD:275368	9/21 (43%)
		zf-H2C2_2	325..349	CDD:290200	10/25 (40%)
		C2H2 Zn finger	341..362	CDD:275368	9/22 (41%)
		zf-H2C2_2	353..377	CDD:290200	10/23 (43%)
		zf-C2H2	368..390	CDD:278523	7/21 (33%)
		C2H2 Zn finger	370..390	CDD:275368	6/19 (32%)
sp3	XP_002934651.1	C2H2 Zn finger	593..615	CDD:275368	9/21 (43%)
		zf-H2C2_2	607..634	CDD:372612	11/26 (42%)
		C2H2 Zn finger	623..645	CDD:275368	9/22 (41%)
		zf-H2C2_2	637..660	CDD:372612	10/23 (43%)
		zf-C2H2	651..673	CDD:333835	7/21 (33%)
		C2H2 Zn finger	653..673	CDD:275368	6/19 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910