DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and Zfp157

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_006504688.1	Gene:	Zfp157 / 72154	MGIID:	1919404	Length:	582	Species:	Mus musculus

Alignment Length:	182	Identity:	53/182 - (29%)
Similarity:	76/182 - (41%)	Gaps:	35/182 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   311 YTCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKERPFKCEICER 375
            |.||.|||.|...:|||||.||||.|:||:||.|.:.||..|.|..|.|. |..|:|::||.|.:
Mouse   282 YVCKDCGKAFFYKSNLTRHHRTHTREKPYECKECRKGFSSKSELTSHHRT-HTGEKPYQCEECGK 345

  Fly   376 CFGQQTNLDRHLKKHESDAVSLSALSGVSERMHCIRRFCENPTEESYFEEIRSFMGKVTQQQQQQ 440
            .|..::.|..|.|.|          ||            |.|.|....::...:...:|:.|:..
Mouse   346 AFYCKSTLRVHQKIH----------SG------------EKPYECKECQKSFYYKSTLTEHQRTH 388

  Fly   441 QQQQQHD------------QQQQQHQSTATSASSSCSSSRDTPTSSHEEADH 480
            ..::.::            |..:.|:.........|...|...:|..|...|
Mouse   389 TGEKPYECKDCGKAFFYKSQLTRHHRIHTGEKPYECEECRKAFSSKSELTAH 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	28/51 (55%)
		zf-C2H2	311..333	CDD:278523	13/21 (62%)
		C2H2 Zn finger	313..333	CDD:275368	12/19 (63%)
		zf-H2C2_2	325..349	CDD:290200	15/23 (65%)
		C2H2 Zn finger	341..362	CDD:275368	9/20 (45%)
		zf-H2C2_2	353..377	CDD:290200	9/23 (39%)
		zf-C2H2	368..390	CDD:278523	7/21 (33%)
		C2H2 Zn finger	370..390	CDD:275368	7/19 (37%)
Zfp157	XP_006504688.1	KRAB	19..79	CDD:214630
		C2H2 Zn finger	173..192	CDD:275368
		COG5048	196..550	CDD:227381	53/182 (29%)
		C2H2 Zn finger	200..220	CDD:275368
		C2H2 Zn finger	228..248	CDD:275368
		C2H2 Zn finger	256..276	CDD:275368
		C2H2 Zn finger	284..304	CDD:275368	12/19 (63%)
		C2H2 Zn finger	312..332	CDD:275368	9/20 (45%)
		C2H2 Zn finger	340..360	CDD:275368	7/19 (37%)
		C2H2 Zn finger	368..388	CDD:275368	2/19 (11%)
		C2H2 Zn finger	396..416	CDD:275368	2/19 (11%)
		C2H2 Zn finger	424..444	CDD:275368	5/17 (29%)
		C2H2 Zn finger	452..472	CDD:275368
		C2H2 Zn finger	480..500	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910