DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and Prdm5

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_038964622.1	Gene:	Prdm5 / 689788	RGDID:	1588700	Length:	599	Species:	Rattus norvegicus

Alignment Length:	178	Identity:	50/178 - (28%)
Similarity:	85/178 - (47%)	Gaps:	35/178 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   276 HPQLQDYQTRRKNKARTAATGGNATPNLPQRNKDRYT------CKFCGKVFPRSANLTRHLRTHT 334
            |.:.:.|:....:||       ..||::.:.:|..:|      |.:||:.|..|..|..|:|:||
  Rat   424 HERHKKYRCELCSKA-------FVTPSVLRSHKKTHTGEKEKVCPYCGQKFASSGTLRVHIRSHT 481

  Fly   335 GEQPYKCKYCERSFSISSNLQRHVRNIHNKERPFKCEICERCFGQQTNLDRHLKKHESD------ 393
            ||:||:|.|||:.||.:..|:.|:|. |.:|:|::|..|.:.|.|:..||.|.:.|..:
  Rat   482 GERPYQCPYCEKGFSKNDGLKMHIRT-HTREKPYQCSECSKAFSQKRGLDEHKRTHTGEKPFQCD 545

  Fly   394 ----AVSLSAL-----------SGVSERMHCIRRFCENPTEESYFEEI 426
                |.||..:           ..::|...|.::|..|...:.:.:.|
  Rat   546 VCDLAFSLKKMLIRHKMTHNPNRPMAECHFCHKKFTRNDYLKVHMDNI 593

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	27/68 (40%)
		zf-C2H2	311..333	CDD:278523	9/27 (33%)
		C2H2 Zn finger	313..333	CDD:275368	8/19 (42%)
		zf-H2C2_2	325..349	CDD:290200	13/23 (57%)
		C2H2 Zn finger	341..362	CDD:275368	9/20 (45%)
		zf-H2C2_2	353..377	CDD:290200	8/23 (35%)
		zf-C2H2	368..390	CDD:278523	7/21 (33%)
		C2H2 Zn finger	370..390	CDD:275368	7/19 (37%)
Prdm5	XP_038964622.1	PR-SET_PRDM5	2..128	CDD:380967
		C2H2 Zn finger	169..190	CDD:275368
		COG5048	186..590	CDD:227381	49/173 (28%)
		C2H2 Zn finger	201..221	CDD:275368
		C2H2 Zn finger	233..256	CDD:275368
		C2H2 Zn finger	266..286	CDD:275368
		C2H2 Zn finger	291..311	CDD:275368
		C2H2 Zn finger	319..339	CDD:275368
		C2H2 Zn finger	347..367	CDD:275368
		C2H2 Zn finger	375..395	CDD:275368
		C2H2 Zn finger	403..420	CDD:275368
		C2H2 Zn finger	432..452	CDD:275368	5/26 (19%)
		C2H2 Zn finger	460..480	CDD:275368	8/19 (42%)
		C2H2 Zn finger	488..508	CDD:275368	9/20 (45%)
		C2H2 Zn finger	516..536	CDD:275368	7/19 (37%)
		C2H2 Zn finger	544..564	CDD:275368	3/19 (16%)
		C2H2 Zn finger	573..594	CDD:275368	4/21 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910