DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and plagx

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001034918.1	Gene:	plagx / 664689	ZFINID:	ZDB-GENE-030131-839	Length:	380	Species:	Danio rerio

Alignment Length:	339	Identity:	79/339 - (23%)
Similarity:	119/339 - (35%)	Gaps:	117/339 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   282 YQTRRKNKARTAATGGNATPNLPQRNKDRYTCKFCGKVFPRSANLTRHLRTHTGEQP-------- 338
            |.||...:...|....:|:.:|        |||.|.:||.....|..||.||||..|
Zfish    31 YNTRLGLRRHVATHATSASSDL--------TCKVCRQVFESMPALLEHLSTHTGRPPPGTVVRER 87

  Fly   339 -YKCKYCERSFSISSNLQRHVRNIHNKERPFKCEICERCFGQQTNLDRHLKKHESDAVSLSAL-- 400
             ::|:.|.|.|....:::||. .:|...|.|.|..|.:.||::.:|.|||||  |.|..|.||
Zfish    88 KHQCERCGRRFFTRKDVRRHA-VVHTGRRDFLCPRCAQRFGRRDHLTRHLKK--SHAQELDALPT 149

  Fly   401 ---------------------------------------SGVSERMHCIRRFCENPTEESYFEEI 426
                                                   ||||...|   .....|        :
Zfish   150 LPIKEEPSPTMCSVGSPKDVTEAFPMAMFNSQGLQSASTSGVSHHHH---GMVSGP--------L 203

  Fly   427 RSFMGKVTQQQQQQQQQQQHDQQQQQHQSTATS---------------------ASSSCSSSRD- 469
            .|.:|.....:..:...||:.|..:...|:.||                     |:.:.:.||.
Zfish   204 SSPVGMGCYLEPNKPPPQQYQQTPRYQPSSTTSYLKAEMENFLTELQCGPMPPQAAVATAVSRPG 268

  Fly   470 --TPTSSHEEADHAPATSTADTAA--PSSSRDQEEEDSQPIMELKRTL----------TSKLFPT 520
              .|.|...::.|....::|.|:|  |:||.:         |:|...|          ::.|..:
Zfish   269 DLLPESLGGQSAHFTLRNSAFTSAEPPASSAN---------MDLSHLLGFLPFGLPPYSTPLGYS 324

  Fly   521 TTADSAMTTPQTTS 534
            ||:.:...:|..||
Zfish   325 TTSAAPAVSPSPTS 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	21/71 (30%)
		zf-C2H2	311..333	CDD:278523	9/21 (43%)
		C2H2 Zn finger	313..333	CDD:275368	8/19 (42%)
		zf-H2C2_2	325..349	CDD:290200	11/32 (34%)
		C2H2 Zn finger	341..362	CDD:275368	6/20 (30%)
		zf-H2C2_2	353..377	CDD:290200	7/23 (30%)
		zf-C2H2	368..390	CDD:278523	10/21 (48%)
		C2H2 Zn finger	370..390	CDD:275368	9/19 (47%)
plagx	NP_001034918.1	C2H2 Zn finger	54..74	CDD:275368	8/19 (42%)
		C2H2 Zn finger	91..111	CDD:275368	6/20 (30%)
		C2H2 Zn finger	119..137	CDD:275368	7/17 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24393
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100