DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and ZFP62

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001166109.1	Gene:	ZFP62 / 643836	HGNCID:	23241	Length:	900	Species:	Homo sapiens

Alignment Length:	163	Identity:	49/163 - (30%)
Similarity:	74/163 - (45%)	Gaps:	39/163 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   276 HPQLQDYQTRRKNKA----------RTAATG--------------GNATPNLPQR---NKDRYTC 313
            ||..:.::.:...|:          ||..||              .||...:.:|   .:..|.|
Human   415 HPGKKAHECKECGKSFSYNSLLLQHRTIHTGERPYVCDVCGKTFRNNAGLKVHRRLHTGEKPYKC 479

  Fly   314 KFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKERPFKCEICERCFG 378
            ..|||.:...::|..|...|.||:||||.|||:||:.||.|::|.| ||.:|:||.|:.|.:.|.
Human   480 DVCGKAYISRSSLKNHKGIHLGEKPYKCSYCEKSFNYSSALEQHKR-IHTREKPFGCDECGKAFR 543

  Fly   379 QQTNLDRHLKKHESDA-----------VSLSAL 400
            ..:.|..|.:.|..:.           :|||:|
Human   544 NNSGLKVHKRIHTGERPYKCEECGKAYISLSSL 576

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	26/65 (40%)
		zf-C2H2	311..333	CDD:278523	7/21 (33%)
		C2H2 Zn finger	313..333	CDD:275368	6/19 (32%)
		zf-H2C2_2	325..349	CDD:290200	13/23 (57%)
		C2H2 Zn finger	341..362	CDD:275368	11/20 (55%)
		zf-H2C2_2	353..377	CDD:290200	10/23 (43%)
		zf-C2H2	368..390	CDD:278523	6/21 (29%)
		C2H2 Zn finger	370..390	CDD:275368	5/19 (26%)
ZFP62	NP_001166109.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..97
		COG5048	125..552	CDD:227381	43/137 (31%)
		C2H2 Zn finger	143..163	CDD:275368
		C2H2 Zn finger	171..191	CDD:275368
		C2H2 Zn finger	199..219	CDD:275368
		C2H2 Zn finger	227..247	CDD:275368
		C2H2 Zn finger	255..275	CDD:275368
		C2H2 Zn finger	283..303	CDD:275368
		C2H2 Zn finger	311..331	CDD:275368
		C2H2 Zn finger	339..359	CDD:275368
		C2H2 Zn finger	367..387	CDD:275368
		C2H2 Zn finger	395..415	CDD:275368	49/163 (30%)
		C2H2 Zn finger	423..443	CDD:275368	3/19 (16%)
		COG5048	447..860	CDD:227381	42/131 (32%)
		C2H2 Zn finger	451..471	CDD:275368	3/19 (16%)
		C2H2 Zn finger	479..499	CDD:275368	6/19 (32%)
		C2H2 Zn finger	507..527	CDD:275368	11/20 (55%)
		C2H2 Zn finger	535..555	CDD:275368	5/19 (26%)
		C2H2 Zn finger	563..583	CDD:275368	4/14 (29%)
		C2H2 Zn finger	591..611	CDD:275368
		C2H2 Zn finger	619..639	CDD:275368
		C2H2 Zn finger	647..667	CDD:275368
		C2H2 Zn finger	675..695	CDD:275368
		C2H2 Zn finger	703..723	CDD:275368
		C2H2 Zn finger	731..751	CDD:275368
		C2H2 Zn finger	759..779	CDD:275368
		C2H2 Zn finger	787..807	CDD:275368
		C2H2 Zn finger	815..834	CDD:275368
		C2H2 Zn finger	842..862	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910