DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10348 and ZNF286A

DIOPT Version :9

Sequence 1:NP_001286059.1 Gene:CG10348 / 35132 FlyBaseID:FBgn0032707 Length:540 Species:Drosophila melanogaster
Sequence 2:NP_001275571.1 Gene:ZNF286A / 57335 HGNCID:13501 Length:564 Species:Homo sapiens


Alignment Length:286 Identity:73/286 - (25%)
Similarity:112/286 - (39%) Gaps:65/286 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   211 LQYRNVFAGVLPGKVNSPAASSSPTGADFPFRHPLKK--------------CELTWPPPTEQLQL 261
            ::::.|..|..|...|.       .|..|..|..|.|              |:.|:   ||.   
Human   302 IRHQRVHTGEKPYTCNE-------CGKSFSHRANLTKHQRTHTRILFECSECKKTF---TES--- 353

  Fly   262 ELPHPNPKLSPVLPHPQLQDYQTRRKNKARTAATGGNATPNLPQR-----NKDRYTCKFCGKVFP 321
                     |.:..|.::  :...|..:......|.|.:.:|.|.     ....|.|..|.|.|.
Human   354 ---------SSLATHQRI--HVGERPYECNECGKGFNRSTHLVQHQLIHTGVKPYECNECDKAFI 407

  Fly   322 RSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKERPFKCEICERCFGQQTNLDRH 386
            .|:.|.:|.||||||:||||:.|.::||..|:|.:|.| :|..|:|::|..|.:.|.|.|:|.:|
Human   408 HSSALIKHQRTHTGEKPYKCQECGKAFSHCSSLTKHQR-VHTGEKPYECSECGKTFSQSTHLVQH 471

  Fly   387 LKKHESDAVSLSALSGVSERMHCIRRFCENPTEESYFEEIRSFMGKVTQQQQQQQQQQQHDQQQQ 451
            .:.|..:.        ..|...|.:.|..:   .::.:..|..:||...:..:..:...|.....
Human   472 QRIHTGEK--------PYECNECGKTFSRS---SNFAKHQRIHIGKKPYKCSECGKAFIHSSALI 525

  Fly   452 QHQSTAT----------SASSSCSSS 467
            |||.|.|          ..|..||||
Human   526 QHQRTHTGEKPFRCNECGKSFKCSSS 551

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10348NP_001286059.1 COG5048 300..>363 CDD:227381 27/67 (40%)
zf-C2H2 311..333 CDD:278523 9/21 (43%)
C2H2 Zn finger 313..333 CDD:275368 8/19 (42%)
zf-H2C2_2 325..349 CDD:290200 13/23 (57%)
C2H2 Zn finger 341..362 CDD:275368 8/20 (40%)
zf-H2C2_2 353..377 CDD:290200 8/23 (35%)
zf-C2H2 368..390 CDD:278523 7/21 (33%)
C2H2 Zn finger 370..390 CDD:275368 7/19 (37%)
ZNF286ANP_001275571.1 KRAB 88..141 CDD:214630
KRAB 88..123 CDD:279668
COG5048 <265..400 CDD:227381 21/121 (17%)
C2H2 Zn finger 288..308 CDD:275368 0/5 (0%)
zf-H2C2_2 301..325 CDD:290200 6/29 (21%)
C2H2 Zn finger 316..336 CDD:275368 6/26 (23%)
C2H2 Zn finger 343..363 CDD:275368 6/36 (17%)
zf-H2C2_2 355..380 CDD:290200 3/26 (12%)
C2H2 Zn finger 371..391 CDD:275368 4/19 (21%)
zf-H2C2_2 383..406 CDD:290200 6/22 (27%)
COG5048 <395..550 CDD:227381 50/166 (30%)
zf-C2H2 397..419 CDD:278523 9/21 (43%)
C2H2 Zn finger 399..419 CDD:275368 8/19 (42%)
zf-H2C2_2 411..436 CDD:290200 14/24 (58%)
C2H2 Zn finger 427..447 CDD:275368 8/20 (40%)
zf-H2C2_2 439..464 CDD:290200 9/25 (36%)
C2H2 Zn finger 455..475 CDD:275368 7/19 (37%)
zf-H2C2_2 467..492 CDD:290200 6/32 (19%)
C2H2 Zn finger 483..503 CDD:275368 3/22 (14%)
zf-H2C2_2 495..518 CDD:290200 3/22 (14%)
C2H2 Zn finger 511..531 CDD:275368 4/19 (21%)
zf-H2C2_2 523..548 CDD:290200 6/24 (25%)
C2H2 Zn finger 539..559 CDD:275368 5/13 (38%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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