DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and znf1085

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_021330858.1	Gene:	znf1085 / 567150	ZFINID:	ZDB-GENE-080218-7	Length:	1074	Species:	Danio rerio

Alignment Length:	152	Identity:	50/152 - (32%)
Similarity:	80/152 - (52%)	Gaps:	7/152 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   308 KDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKERPFKCEI 372
            |..:||..|||.|.:|:.|.||.|.||||:|:.|..|.:||:.||:|.:|:| ||..|:||.|..
Zfish   568 KTPFTCTQCGKSFSQSSYLNRHTRIHTGEKPFTCTLCGKSFNRSSHLNKHMR-IHTGEKPFTCTQ 631

  Fly   373 CERCFGQQTNLDRHLKKHESDAVSLSALSGV------SERMHCIRRFCENPTEESYFEEIRSFMG 431
            |.:.|.|:.||..|::.|..:........|.      |.:.|.|..|.:..:|:...||..:...
Zfish   632 CGKSFSQKQNLTIHMRIHTGEKPYTCTECGKSFPHTGSLKHHMIMAFIKEESEDVKIEETFTVKQ 696

  Fly   432 KVTQQQQQQQQQQQHDQQQQQH 453
            :..|:|....::.:..::::.|
Zfish   697 EDLQEQTDLIEENEGRKEEEHH 718

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	27/54 (50%)
		zf-C2H2	311..333	CDD:278523	11/21 (52%)
		C2H2 Zn finger	313..333	CDD:275368	10/19 (53%)
		zf-H2C2_2	325..349	CDD:290200	12/23 (52%)
		C2H2 Zn finger	341..362	CDD:275368	9/20 (45%)
		zf-H2C2_2	353..377	CDD:290200	10/23 (43%)
		zf-C2H2	368..390	CDD:278523	8/21 (38%)
		C2H2 Zn finger	370..390	CDD:275368	7/19 (37%)
znf1085	XP_021330858.1	COG5048	39..444	CDD:227381
		C2H2 Zn finger	41..61	CDD:275368
		C2H2 Zn finger	69..89	CDD:275368
		C2H2 Zn finger	97..117	CDD:275368
		C2H2 Zn finger	125..145	CDD:275368
		C2H2 Zn finger	153..173	CDD:275368
		C2H2 Zn finger	181..201	CDD:275368
		C2H2 Zn finger	209..229	CDD:275368
		C2H2 Zn finger	237..257	CDD:275368
		COG5048	261..676	CDD:227381	42/108 (39%)
		C2H2 Zn finger	265..285	CDD:275368
		C2H2 Zn finger	293..313	CDD:275368
		C2H2 Zn finger	321..341	CDD:275368
		C2H2 Zn finger	349..369	CDD:275368
		C2H2 Zn finger	377..397	CDD:275368
		C2H2 Zn finger	405..425	CDD:275368
		C2H2 Zn finger	433..453	CDD:275368
		C2H2 Zn finger	461..481	CDD:275368
		C2H2 Zn finger	489..509	CDD:275368
		C2H2 Zn finger	517..537	CDD:275368
		C2H2 Zn finger	545..565	CDD:275368
		C2H2 Zn finger	573..593	CDD:275368	10/19 (53%)
		COG5048	597..1013	CDD:227381	34/123 (28%)
		C2H2 Zn finger	601..621	CDD:275368	9/20 (45%)
		C2H2 Zn finger	629..649	CDD:275368	7/19 (37%)
		C2H2 Zn finger	657..674	CDD:275368	2/16 (13%)
		C2H2 Zn finger	743..763	CDD:275368
		C2H2 Zn finger	771..791	CDD:275368
		C2H2 Zn finger	799..819	CDD:275368
		C2H2 Zn finger	827..847	CDD:275368
		C2H2 Zn finger	855..875	CDD:275368
		C2H2 Zn finger	883..903	CDD:275368
		C2H2 Zn finger	911..931	CDD:275368
		C2H2 Zn finger	939..959	CDD:275368
		C2H2 Zn finger	967..987	CDD:275368
		C2H2 Zn finger	995..1015	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910