DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and AgaP_AGAP011407

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_001689066.1	Gene:	AgaP_AGAP011407 / 5667959	VectorBaseID:	AGAP011407	Length:	257	Species:	Anopheles gambiae

Alignment Length:	332	Identity:	65/332 - (19%)
Similarity:	102/332 - (30%)	Gaps:	119/332 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 HQ------TLNHHAKGKRRSSFDQPLDLRLAHKR-KTDLVDQGPMEDENSNLIMFASELAVAQQK 132
            ||      |..:|...|.....| ||::::...| :|:|.|:....:.|.|.....|...:|.:.
Mosquito    25 HQLCVGPSTSENHGLAKNTQDVD-PLEVQIEVLRVETELFDEDTFVNGNQNTSTVPSHQEIATKN 88

  Fly   133 EKELNNNHIAASLADLGFDMSRKMLRALREGGAGGGGGGGGGGGGGGGPPNAPPLTPPQCSIPAV 197
            ..:.:.|.||.                                       |.|         ||.
Mosquito    89 NDQYSANCIAI---------------------------------------NEP---------PAE 105

  Fly   198 HPTLLEAMTKNLPLQYRNVFAGVLPGKVNSPAASSSPTGADFPFRHPLKKCELTW----PPPT-- 256
            ..|:.:|                      ..:...:|...||           ||    ..|.
Mosquito   106 RLTVRQA----------------------PDSEKETPNDDDF-----------TWHESETDPARD 137

  Fly   257 -EQLQLELPHPNPKLSPVLPHPQLQDYQTRR--KNKARTAATGGNATPNLPQRNKDRYTCKFCGK 318
             :|..:....||.|.:..       :..|||  ..:|::::|||.:.         |..|..||.
Mosquito   138 GKQKLVRKKRPNRKRAGA-------EQITRRDPAREAKSSSTGGRSA---------RVLCSICGT 186

  Fly   319 VFPRSANLTRHLRTHTGEQPYK--CKYCERSFSISSNLQRHVRNIHNKERPFKCEICERCFGQQT 381
            ..   :||..|...|..:...|  |.:|....:...||.||:..:|.|.....||||.:.|....
Mosquito   187 FV---SNLNFHQNYHHAKTSIKLSCPHCPAKITHQKNLTRHINTVHLKIVEKTCEICGKEFTTNN 248

  Fly   382 NLDRHLK 388
            :...|::
Mosquito   249 SYVSHMR 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	15/64 (23%)
		zf-C2H2	311..333	CDD:278523	6/21 (29%)
		C2H2 Zn finger	313..333	CDD:275368	6/19 (32%)
		zf-H2C2_2	325..349	CDD:290200	7/25 (28%)
		C2H2 Zn finger	341..362	CDD:275368	6/20 (30%)
		zf-H2C2_2	353..377	CDD:290200	10/23 (43%)
		zf-C2H2	368..390	CDD:278523	6/21 (29%)
		C2H2 Zn finger	370..390	CDD:275368	6/19 (32%)
AgaP_AGAP011407	XP_001689066.1	C2H2 Zn finger	181..198	CDD:275368	6/19 (32%)
		C2H2 Zn finger	208..229	CDD:275368	6/20 (30%)
		C2H2 Zn finger	237..256	CDD:275368	6/19 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910