DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10348 and prdm14

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_005162704.1	Gene:	prdm14 / 563151	ZFINID:	ZDB-GENE-030131-2709	Length:	568	Species:	Danio rerio

Alignment Length:	180	Identity:	52/180 - (28%)
Similarity:	83/180 - (46%)	Gaps:	38/180 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   311 YTCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKERPFKCEICER 375
            :.|..|||.|.:|::|.:|:|.|:||:||||.||.::|:.||.|:.|:|. |:.||||||:.|.:
Zfish   409 HKCSVCGKSFSQSSSLNKHMRVHSGERPYKCVYCNKAFTASSILRTHIRQ-HSGERPFKCKHCGK 472

  Fly   376 CFGQQTNLDRHLKK-HESDAVSLSALSGVSERMHCIRRFCENPTEESYFEEIRSFMGKVTQQQQQ 439
            .|......|.|::: |..|           :::.|                  ...|...|:.|:
Zfish   473 AFASHAAHDSHVRRTHAKD-----------KQLSC------------------DVCGATFQEAQE 508

  Fly   440 QQQQQQHDQQQQQHQSTATSASSSCSSSRDTPTSSHEEADHAPATSTADT 489
            .:      ...:.|:......||....:.:....|.:|:.|| .|..|||
Zfish   509 LK------YHMKAHKKRPLLESSVVPPADENALFSTKESLHA-QTQLADT 551

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	24/51 (47%)
		zf-C2H2	311..333	CDD:278523	9/21 (43%)
		C2H2 Zn finger	313..333	CDD:275368	9/19 (47%)
		zf-H2C2_2	325..349	CDD:290200	12/23 (52%)
		C2H2 Zn finger	341..362	CDD:275368	9/20 (45%)
		zf-H2C2_2	353..377	CDD:290200	11/23 (48%)
		zf-C2H2	368..390	CDD:278523	7/22 (32%)
		C2H2 Zn finger	370..390	CDD:275368	5/20 (25%)
prdm14	XP_005162704.1	SET	214..316	CDD:279228
		C2H2 Zn finger	382..401	CDD:275368
		zf-C2H2	409..431	CDD:278523	9/21 (43%)
		C2H2 Zn finger	411..431	CDD:275368	9/19 (47%)
		zf-H2C2_2	423..447	CDD:290200	12/23 (52%)
		C2H2 Zn finger	439..459	CDD:275368	9/20 (45%)
		zf-H2C2_2	452..476	CDD:290200	12/24 (50%)
		C2H2 Zn finger	467..488	CDD:275368	5/20 (25%)
		C2H2 Zn finger	496..516	CDD:275368	4/43 (9%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910