DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and si:ch211-117k10.3

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_684045.1	Gene:	si:ch211-117k10.3 / 556200	ZFINID:	ZDB-GENE-141212-273	Length:	371	Species:	Danio rerio

Alignment Length:	262	Identity:	64/262 - (24%)
Similarity:	99/262 - (37%)	Gaps:	87/262 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   181 PPNAPPLTPPQCSIPAVHPTLLEAMTKNLPLQYRNVFAGVLPGKVNSPAASSSP-TGADFPFR-H 243
            ||::|..:..:.|:.|...|     |::                ||:.|:::|. .||.|..: .
Zfish   132 PPSSPGESEEKSSMMATSQT-----TQS----------------VNATASATSVLVGAPFVLQLQ 175

  Fly   244 PLKKCELTWPPPTEQLQLELPHPNPK------------------------LSPVLPHPQLQDYQT 284
            ||            ||...||.|:.:                        |||.:|...|.....
Zfish   176 PL------------QLSHALPQPDNQSGVAGGLRVAHLVLGVQGTQNITLLSPQVPSATLLPIMG 228

  Fly   285 RRKNK-------------ARTAATGGNA-----TPNLPQRNKDR----YTCKF--CGKVFPRSAN 325
            ...|:             .|.....|..     ||. |.|:...    :.|..  |.|::.:|::
Zfish   229 EAVNQDQKYVKIAPLPIAVRAVGIAGAGLVKAITPR-PSRSTTETLRVHKCSHPGCEKMYTKSSH 292

  Fly   326 LTRHLRTHTGEQPYKCKY--CERSFSISSNLQRHVRNIHNKERPFKCEICERCFGQQTNLDRHLK 388
            |..|.|.||||:||.|.:  |...||.|..|.|| |..|:..:|::|.:|::.|.:..:|.:|.|
Zfish   293 LKAHFRRHTGEKPYLCSWPDCGWRFSRSDELSRH-RRSHSGVKPYECTMCDKKFARSDHLSKHTK 356

  Fly   389 KH 390
            .|
Zfish   357 VH 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	26/70 (37%)
		zf-C2H2	311..333	CDD:278523	7/23 (30%)
		C2H2 Zn finger	313..333	CDD:275368	7/21 (33%)
		zf-H2C2_2	325..349	CDD:290200	11/25 (44%)
		C2H2 Zn finger	341..362	CDD:275368	9/22 (41%)
		zf-H2C2_2	353..377	CDD:290200	8/23 (35%)
		zf-C2H2	368..390	CDD:278523	6/21 (29%)
		C2H2 Zn finger	370..390	CDD:275368	6/19 (32%)
si:ch211-117k10.3	XP_684045.1	zf-C2H2	276..300	CDD:278523	7/23 (30%)
		zf-C2H2_8	278..357	CDD:292531	29/79 (37%)
		C2H2 Zn finger	278..300	CDD:275368	7/21 (33%)
		zf-H2C2_2	292..319	CDD:290200	12/26 (46%)
		C2H2 Zn finger	308..330	CDD:275368	9/22 (41%)
		zf-H2C2_2	322..347	CDD:290200	9/25 (36%)
		C2H2 Zn finger	338..358	CDD:275368	6/19 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910