DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10348 and znf989

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001018578.1	Gene:	znf989 / 553777	ZFINID:	ZDB-GENE-050522-337	Length:	381	Species:	Danio rerio

Alignment Length:	232	Identity:	59/232 - (25%)
Similarity:	106/232 - (45%)	Gaps:	37/232 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   256 TEQLQLE----LPHPNPKLSPVL-----PHPQLQDYQTRRKNKARTAATGGNATP--NLPQR--N 307
            :|.|::|    :.|.:|:....|     ....|.:.:..:..:.:...|...:||  :||.:  .
Zfish     8 SEDLKIEDTFSVKHEDPEEQTELMVLKEEFQDLNEMEESQCERHQDLTTDEKSTPKKSLPHKRVQ 72

  Fly   308 KDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKERPFKCEI 372
            |:.:||..|||.|.:..:|..|:|.|||::.:.|..|.:||:..|.:..|:| :|..||.:.|..
Zfish    73 KNNFTCCVCGKCFSQRHSLKVHMRIHTGDKLFTCDQCGKSFTQKSKIDVHMR-VHTSERHYSCPQ 136

  Fly   373 CERCFGQQTNLDRHLKKHESDAVSLSALSGVSER----MHCIRRFCENPTEESYFEEIRSFMGK- 432
            |.:.|.|:.:|..|::.|          ||  |:    ..|.:||.:....:|:| .|.|  |:
Zfish   137 CAKGFRQKQHLKLHMRIH----------SG--EKPFPCNQCGKRFNQLQALQSHF-TIHS--GER 186

  Fly   433 ---VTQQQQQQQQQQQHDQQQQQHQSTATSASSSCSS 466
               .||.::..:|:...::..:.|........|.|.:
Zfish   187 PYACTQCEKSFRQRPSLEKHLKVHSREKPFTCSQCGN 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	24/66 (36%)
		zf-C2H2	311..333	CDD:278523	9/21 (43%)
		C2H2 Zn finger	313..333	CDD:275368	8/19 (42%)
		zf-H2C2_2	325..349	CDD:290200	9/23 (39%)
		C2H2 Zn finger	341..362	CDD:275368	7/20 (35%)
		zf-H2C2_2	353..377	CDD:290200	7/23 (30%)
		zf-C2H2	368..390	CDD:278523	6/21 (29%)
		C2H2 Zn finger	370..390	CDD:275368	6/19 (32%)
znf989	NP_001018578.1	C2H2 Zn finger	78..98	CDD:275368	8/19 (42%)
		zf-H2C2_2	90..115	CDD:290200	10/24 (42%)
		C2H2 Zn finger	106..126	CDD:275368	7/20 (35%)
		C2H2 Zn finger	134..154	CDD:275368	6/19 (32%)
		zf-H2C2_2	146..171	CDD:290200	9/36 (25%)
		COG5048	<149..377	CDD:227381	19/90 (21%)
		C2H2 Zn finger	162..182	CDD:275368	5/20 (25%)
		C2H2 Zn finger	190..210	CDD:275368	3/19 (16%)
		C2H2 Zn finger	218..238	CDD:275368	2/6 (33%)
		zf-H2C2_2	231..255	CDD:290200
		C2H2 Zn finger	246..266	CDD:275368
		zf-H2C2_2	258..283	CDD:290200
		C2H2 Zn finger	274..294	CDD:275368
		zf-H2C2_2	290..311	CDD:290200
		C2H2 Zn finger	302..322	CDD:275368
		zf-H2C2_2	314..339	CDD:290200
		C2H2 Zn finger	330..350	CDD:275368
		C2H2 Zn finger	356..376	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910