DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and klf4

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001017280.1	Gene:	klf4 / 550034	XenbaseID:	XB-GENE-1015049	Length:	407	Species:	Xenopus tropicalis

Alignment Length:	409	Identity:	102/409 - (24%)
Similarity:	153/409 - (37%)	Gaps:	116/409 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 ASSASVAATSSS----STSPTTTSA--TTTGRLQHQHSHQQHQ---TLNHHAKGKRRSSFDQPLD 95
            :||:|.:.|:||    :|.|.|.||  :||....:|....|..   ||.::|:....||
Frog    56 SSSSSSSVTASSPPPPATLPDTMSALSSTTCNFVYQVRCPQESSGGTLMYNARDPTMSS------ 114

  Fly    96 LRLAHKRKTDLVDQGPMEDENSNLIMFASELA--------VAQQKEKELNNNHI---AASLADLG 149
               |.....|:.|..|...       |.:||.        :.||.:..|....:   ..|:.|.|
Frog   115 ---ATFNLADINDVSPSGG-------FVAELMRPDLDPVFMQQQPQASLQGKFVLKTTVSMGDYG 169

  Fly   150 FDMSRKMLRALREGGAGGGGGGGGGGGGGGGPPNAPPLTPPQCSIPAVHPTLLE----AMTKNLP 210
            ..:|      :|:..:|...                ||:.....:|.|...:.:    :.|...|
Frog   170 QTIS------VRKNNSGIDS----------------PLSYTTHQLPRVCQKIKQEPSSSCTSACP 212

  Fly   211 L--------QYRNVFAG-VLPGKVNSPAASSSPTGAD-FPFRHPLKKCELTWPP----------- 254
            :        ..|...|| .||.:.|...:.....|.| ......|....|..||
Frog   213 MDGQGQQSQSMREFQAGRGLPIRTNQSLSPEELMGRDCHSSSQTLSHSSLPIPPAYHTSASFSHF 277

  Fly   255 PTEQLQLELPHPNPKLSPVLPHPQLQDYQTRRKNKARTAATGG---------NATPNLPQRNKDR 310
            .::|.|.:||            |....||       ....|||         ....:.|::....
Frog   278 TSDQPQTQLP------------PTQLQYQ-------ELLTTGGCIPEESKPKRGRKSWPRKRTAT 323

  Fly   311 YTCKF--CGKVFPRSANLTRHLRTHTGEQPYKCKY--CERSFSISSNLQRHVRNIHNKERPFKCE 371
            :||::  |||.:.:|::|..||||||||:||.|.:  |...|:.|..|.||.|. |...|||:|:
Frog   324 HTCEYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWEGCGWKFARSDELTRHYRK-HTGHRPFQCQ 387

  Fly   372 ICERCFGQQTNLDRHLKKH 390
            .|:|.|.:..:|..|:|:|
Frog   388 RCDRAFSRSDHLALHMKRH 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	26/66 (39%)
		zf-C2H2	311..333	CDD:278523	10/23 (43%)
		C2H2 Zn finger	313..333	CDD:275368	9/21 (43%)
		zf-H2C2_2	325..349	CDD:290200	13/25 (52%)
		C2H2 Zn finger	341..362	CDD:275368	8/22 (36%)
		zf-H2C2_2	353..377	CDD:290200	11/23 (48%)
		zf-C2H2	368..390	CDD:278523	8/21 (38%)
		C2H2 Zn finger	370..390	CDD:275368	7/19 (37%)
klf4	NP_001017280.1	zf-C2H2	324..348	CDD:333835	10/23 (43%)
		C2H2 Zn finger	326..348	CDD:275368	9/21 (43%)
		C2H2 Zn finger	356..378	CDD:275368	8/22 (36%)
		zf-H2C2_2	370..395	CDD:372612	12/25 (48%)
		C2H2 Zn finger	386..406	CDD:275368	7/19 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910