DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10348 and fezf2

DIOPT Version :9

Sequence 1:NP_001286059.1 Gene:CG10348 / 35132 FlyBaseID:FBgn0032707 Length:540 Species:Drosophila melanogaster
Sequence 2:NP_001016305.1 Gene:fezf2 / 549059 XenbaseID:XB-GENE-1006432 Length:435 Species:Xenopus tropicalis


Alignment Length:324 Identity:81/324 - (25%)
Similarity:117/324 - (36%) Gaps:82/324 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   139 NHIAASLADLGFDMSRKMLRALREGGAGGGGGGGGGGGGGGGPPNAPPL----TPPQCSIPAVHP 199
            |..:|:...|.|.:.|.|.:......|       ......|..|.|..:    :|..|.|| :..
 Frog    19 NGASATPKSLAFSIERIMAKTSEPKAA-------AFQPSQGLDPGAKKMLNLCSPLPCMIP-IQS 75

  Fly   200 TLLEAMTKNLPLQYRNVFAGVLPGKVNSPAA-SSSPTGA----DFPFRHPLKKCELTWPPPTEQL 259
            ...:..:|.| |.|..::...|.|.|.||:. ..|..|.    |....|.:........|.....
 Frog    76 LAYDVHSKAL-LNYSELWKSSLRGSVCSPSGLCKSNCGICCKNDLNMGHTVLPGSRVIKPQVINQ 139

  Fly   260 QLELP---------------HP--------------------------------NPKLS------ 271
            .:.||               ||                                |.|||      
 Frog   140 TVGLPTNGSLYYFNYLDSSFHPPEILSGQLLSSSLINAQSQATLSAQQKLFLLENAKLSGLAPEK 204

  Fly   272 ---PVLPHPQL---QDYQTRRKNKARTAATGGNATPNLPQRNKDR----YTCKFCGKVFPRSANL 326
               |..||.:.   |..|..::|.|.:|...|.....|...:.:.    :||:.|||||....||
 Frog   205 FPNPQYPHKERLPGQLDQVMKENSALSADRSGKIHSKLGANSAEGKPKIFTCEVCGKVFNAHYNL 269

  Fly   327 TRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKERPFKCEICERCFGQQTNLDRHLKKH 390
            |||:..|||.:|:.||.|.:.|..:|.|.|| :.||.:|:|.||..|.:.|.:.:.|:.|::.|
 Frog   270 TRHMPVHTGARPFVCKVCGKGFRQASTLCRH-KIIHTQEKPHKCNQCGKAFNRSSTLNTHIRIH 332

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10348NP_001286059.1 COG5048 300..>363 CDD:227381 26/66 (39%)
zf-C2H2 311..333 CDD:278523 12/21 (57%)
C2H2 Zn finger 313..333 CDD:275368 11/19 (58%)
zf-H2C2_2 325..349 CDD:290200 12/23 (52%)
C2H2 Zn finger 341..362 CDD:275368 8/20 (40%)
zf-H2C2_2 353..377 CDD:290200 10/23 (43%)
zf-C2H2 368..390 CDD:278523 6/21 (29%)
C2H2 Zn finger 370..390 CDD:275368 5/19 (26%)
fezf2NP_001016305.1 Engrailed homology 1 repressor. /evidence=ECO:0000250 27..42 4/14 (29%)
COG5048 <239..401 CDD:227381 36/95 (38%)
C2H2 Zn finger 256..276 CDD:275368 11/19 (58%)
C2H2 Zn finger 284..304 CDD:275368 8/20 (40%)
C2H2 Zn finger 312..332 CDD:275368 5/19 (26%)
C2H2 Zn finger 340..360 CDD:275368
C2H2 Zn finger 368..388 CDD:275368
C2H2 Zn finger 396..414 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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