DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and zgc:113294

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001013567.1	Gene:	zgc:113294 / 541422	ZFINID:	ZDB-GENE-050320-124	Length:	332	Species:	Danio rerio

Alignment Length:	186	Identity:	55/186 - (29%)
Similarity:	91/186 - (48%)	Gaps:	35/186 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   239 FPFRH-PLKKCELTWPPPTEQLQLELPHPNPK-----LSPVLPHPQLQDY--------------- 282
            ||.:| .:::..:.:..|.||.:..:|   ||     .:.:..:.|.::|
Zfish    17 FPVKHEEIEEFIIKYEDPEEQTEDLIP---PKEEGQDQNEMEENDQYEEYCDFTPEEDSEQTNAS 78

  Fly   283 --QTRRKNKARTAATGGNA-------TPNLPQRNKDR-YTCKFCGKVFPRSANLTRHLRTHTGEQ 337
              :|.||.|:.|....|.:       ..::...|.:: |||:.|||.|....||..|:||||.|:
Zfish    79 SEETARKAKSNTCHQCGRSFTRKQYLIEHMTIHNGEKPYTCQQCGKSFTWKQNLKIHMRTHTDEK 143

  Fly   338 PYKCKYCERSFSISSNLQRHVRNIHNKERPFKCEICERCFGQQTNLDRHLKKHESD 393
            ||.|..|.:||:.:.||.:|: .:|..|:|:.||.|.:||.:|.||..|::.|..:
Zfish   144 PYTCHQCGKSFARNQNLSKHM-GVHTGEKPYTCECCGKCFTRQQNLTGHMRVHTGE 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	25/63 (40%)
		zf-C2H2	311..333	CDD:278523	11/21 (52%)
		C2H2 Zn finger	313..333	CDD:275368	9/19 (47%)
		zf-H2C2_2	325..349	CDD:290200	13/23 (57%)
		C2H2 Zn finger	341..362	CDD:275368	7/20 (35%)
		zf-H2C2_2	353..377	CDD:290200	9/23 (39%)
		zf-C2H2	368..390	CDD:278523	9/21 (43%)
		C2H2 Zn finger	370..390	CDD:275368	9/19 (47%)
zgc:113294	NP_001013567.1	COG5048	<71..207	CDD:227381	44/129 (34%)
		C2H2 Zn finger	91..111	CDD:275368	1/19 (5%)
		zf-H2C2_2	103..127	CDD:290200	7/23 (30%)
		C2H2 Zn finger	119..139	CDD:275368	9/19 (47%)
		zf-H2C2_2	131..156	CDD:290200	14/24 (58%)
		C2H2 Zn finger	147..167	CDD:275368	7/20 (35%)
		zf-H2C2_2	159..184	CDD:290200	11/25 (44%)
		C2H2 Zn finger	175..195	CDD:275368	9/19 (47%)
		zf-H2C2_2	187..211	CDD:290200	4/12 (33%)
		C2H2 Zn finger	203..223	CDD:275368
		C2H2 Zn finger	231..251	CDD:275368
		COG5048	259..>318	CDD:227381
		C2H2 Zn finger	259..279	CDD:275368
		zf-H2C2_2	272..296	CDD:290200
		C2H2 Zn finger	287..307	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910