DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and ich

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001262393.1	Gene:	ich / 41069	FlyBaseID:	FBgn0286204	Length:	592	Species:	Drosophila melanogaster

Alignment Length:	456	Identity:	92/456 - (20%)
Similarity:	145/456 - (31%)	Gaps:	167/456 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 LIPTSYISHVPYDLA------SSASVAATSSSSTSPTTTSATTTGRLQHQHSHQQHQTLNHHAKG 84
            |...|.:....|.:|      .|.|.:|.:.:.:.|:..:.|...::..          :.|..|
  Fly   183 LFADSQLDSKLYSVADSCVMNGSGSGSAANGNGSGPSIATLTPIDQVAD----------SLHNSG 237

  Fly    85 KRRSSFDQPLDLRLAHKRKTDLVDQGPMEDENSNLIMFASELAVAQQKEKELNN----------- 138
            .|            .:|..|:.||...::|..:.:....::..|..|.:|:.||
  Fly   238 VR------------IYKDLTEYVDMNSIDDIAAIIGSAIADTTVPNQLDKDDNNDTRDSWMDLDA 290

  Fly   139 ----NHIAA-----------SLAD-------LGFDMSRKMLRAL-----------------REGG 164
                |.|..           ||.|       |....|...|::|                 ..|.
  Fly   291 WIDGNCIQQESAKVLVSQQDSLGDFILPHSPLPMHASSSTLQSLLSHGYMPLLQNRLQNGPPNGN 355

  Fly   165 AGGGGGGGGGGGGGGGPPNAP----------PLTPPQCSIPA-------------VHPTLLEAMT 206
            :.|||||...|.|..|.|.||          ..|...||.|.             ::|..|...|
  Fly   356 SSGGGGGANQGAGIKGDPQAPTSTSYCNELAAATSSSCSPPGSVVSTTDNPNGLMINPRYLSNPT 420

  Fly   207 KN------------------LPLQYRNVFAGVLPGKVNSP-AASSSPTGADFPFRHPLKKCELTW 252
            .|                  |.|:...:.:..|.|  |.| ..::|.||::.....|..|...:.
  Fly   421 NNQATGNLHQQGGYSMQASGLSLKDNGLCSPDLLG--NYPHTTTASTTGSEMRTGAPKAKRSRSQ 483

  Fly   253 PPPTEQLQLELPHPNPKLSPVLPHPQLQDYQTRRKNKARTAATGGNATPNLPQ------------ 305
            ....:|.|                 |.|..|.::.:        |...|..||
  Fly   484 KKSNQQQQ-----------------QQQQQQQQQGD--------GGGQPTTPQMSAISPSGFSAS 523

  Fly   306 -------RNKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHN 363
                   :.|..:.|..|.:.|...:|:..||||||||:|::|..|.::|...::|.:| :.||.
  Fly   524 DLSGLLGKEKPVHRCSICNRGFLNKSNIKVHLRTHTGEKPFRCDVCAKAFRQKAHLLKH-QQIHK 587

  Fly   364 K 364
            :
  Fly   588 R 588

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	23/81 (28%)
		zf-C2H2	311..333	CDD:278523	7/21 (33%)
		C2H2 Zn finger	313..333	CDD:275368	7/19 (37%)
		zf-H2C2_2	325..349	CDD:290200	12/23 (52%)
		C2H2 Zn finger	341..362	CDD:275368	5/20 (25%)
		zf-H2C2_2	353..377	CDD:290200	4/12 (33%)
		zf-C2H2	368..390	CDD:278523
		C2H2 Zn finger	370..390	CDD:275368
ich	NP_001262393.1	C2H2 Zn finger	538..558	CDD:275368	7/19 (37%)
		zf-H2C2_2	550..575	CDD:316026	13/24 (54%)
		C2H2 Zn finger	566..586	CDD:275368	5/20 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24393
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100