DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and sp5

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_989092.1	Gene:	sp5 / 394696	XenbaseID:	XB-GENE-1217606	Length:	374	Species:	Xenopus tropicalis

Alignment Length:	433	Identity:	95/433 - (21%)
Similarity:	142/433 - (32%)	Gaps:	146/433 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 HSPRKMLPSPKQGCVYPALGLIPTSYISHVPYD--LASSA--------SVAATSSSSTSPTTTSA 60
            |||..:|.:.......|..|  |..:| ..|||  :.|.:        .::|.||....|.....
Frog    30 HSPLALLAATCSRIGQPGTG--PADFI-QFPYDPTIGSPSRIFHPWTNEISAHSSGGIQPHNGIG 91

  Fly    61 TTTGRLQHQHSHQQHQTLNHHAKGKRRSSFDQPLDLRLAHKRKTDLVDQGPMEDENSNLIMFASE 125
            .:|.:.| ..||.|...:.|..      ....|.|....:       |..||:       |....
Frog    92 LSTSKTQ-LASHIQSSFVTHEL------PLTPPADPSYPY-------DYSPMK-------MLPPP 135

  Fly   126 LAVAQQKEKELNNNHIAASLADLGFDMSRKMLRALREGGAGGGGGGGGGGGGGGGPPNAP--PLT 188
            :|..|.                                              |...|..|  |..
Frog   136 MAAFQT----------------------------------------------GCQSPYVPAVPYA 154

  Fly   189 PPQCSIPAVHPTLLEAMTKNLPLQYRNVFAGVLPGKVN----SPAASSSPTGADFPFRHPLKKCE 249
            ||.....|:|                    |.:|...|    .|...|.....|.|:
Frog   155 PPAPITSALH--------------------GFVPSHSNLIHQQPRQLSPNPAEDMPW-------- 191

  Fly   250 LTW----PPPTEQLQLELPHPNPKL----SPVLPHPQLQDYQT---------------RRKNKAR 291
              |    ..|..... .:|||:.:.    |.||.|.....|||               ||..:.|
Frog   192 --WSIQQATPVAHAS-TIPHPHHRFPIQRSLVLGHSDFAQYQTQIAALLQTKSPLATARRCRRCR 253

  Fly   292 TAATGGNATPNLPQRNKDRYTCKF--CGKVFPRSANLTRHLRTHTGEQPYKCK--YCERSFSISS 352
            ......::.|:...:.| ::.|..  ||||:.::::|..|||.|:||:|:.|.  :|.:||:.|.
Frog   254 CPNCQTSSGPDEAGKKK-QHICHIPGCGKVYGKTSHLKAHLRWHSGERPFICNWLFCGKSFTRSD 317

  Fly   353 NLQRHVRNIHNKERPFKCEICERCFGQQTNLDRHLKKHESDAV 395
            .||||:|. |..|:.|.|..|.:.|.:..:|.:|:|.|::..:
Frog   318 ELQRHLRT-HTGEKRFVCPECGKRFMRSDHLAKHVKTHQNKKI 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	25/66 (38%)
		zf-C2H2	311..333	CDD:278523	9/23 (39%)
		C2H2 Zn finger	313..333	CDD:275368	9/21 (43%)
		zf-H2C2_2	325..349	CDD:290200	11/25 (44%)
		C2H2 Zn finger	341..362	CDD:275368	10/22 (45%)
		zf-H2C2_2	353..377	CDD:290200	10/23 (43%)
		zf-C2H2	368..390	CDD:278523	7/21 (33%)
		C2H2 Zn finger	370..390	CDD:275368	6/19 (32%)
sp5	NP_989092.1	C2H2 Zn finger	277..296	CDD:275368	8/18 (44%)
		zf-C2H2	302..326	CDD:333835	10/24 (42%)
		C2H2 Zn finger	304..326	CDD:275368	10/22 (45%)
		zf-H2C2_2	318..341	CDD:372612	10/23 (43%)
		zf-C2H2	332..354	CDD:333835	7/21 (33%)
		C2H2 Zn finger	334..354	CDD:275368	6/19 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910