DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and CG42741

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_611747.2	Gene:	CG42741 / 37654	FlyBaseID:	FBgn0261705	Length:	362	Species:	Drosophila melanogaster

Alignment Length:	393	Identity:	88/393 - (22%)
Similarity:	143/393 - (36%)	Gaps:	94/393 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 PYDLASSASVAATSSSSTSPTTTSATTTGRLQHQHSHQQHQTLNHHAKGKRRSSFDQPLDLRLAH 100
            |.||:..:..|:||..|:|.:...::....:.:.         |....|...||.....
  Fly    26 PVDLSLRSPRASTSHGSSSSSYKFSSANKAVGYS---------NGKPGGSSGSSSSSGF------ 75

  Fly   101 KRKTDLVDQGPMEDENSNLIMFASELAVAQQKEKELNNNHIAASLADLGFDMSRKMLRALREGGA 165
                     |.....:|:|..||     |||:::...::.::.......|..|.......|..|:
  Fly    76 ---------GAGSAGSSSLGAFA-----AQQQQQLYASSGVSKLPFSPFFAASPFFFTYRRISGS 126

  Fly   166 GGGGG------------------GGGGGGGGGGPPNAPPLTPPQCSIPAVHPTLLEAMTKNLPLQ 212
            |.|.|                  .|...||.|...|:......:.|        |.::.|| |.:
  Fly   127 GSGNGTGSVSVKQEDNNNSCSYNNGSSSGGAGSAANSMQDYESKFS--------LLSLFKN-PYK 182

  Fly   213 YRNVFAGVLPGKVNSPAASSSPTGADFPFRHPLKKCELTWPPPTEQLQLELPHPNPKLSPVLPHP 277
            :        .|.....:..:||||..   ..||....    .|:.:.......|:..|:|..  .
  Fly   183 F--------AGGDGQASRKTSPTGGS---SKPLASNS----SPSWKSYAGSGSPHAALNPAF--G 230

  Fly   278 QLQDYQTRRKNKARTAATGG----------------NATPNLPQRNKDRYTC--KFCGKVFPRSA 324
            .:....||:.|.:.:....|                |...|...:|:..:.|  :.|.||:.:|:
  Fly   231 GMGRGATRKDNSSFSGINFGGGGSAFGFTTSSDSMANGGYNDLSKNRKVHKCDTEGCDKVYTKSS 295

  Fly   325 NLTRHLRTHTGEQPYKCKY--CERSFSISSNLQRHVRNIHNKERPFKCEICERCFGQQTNLDRHL 387
            :|..|.||||||:||.|.:  |...|:.|..|.||.|. |...:||:|::|.|.|.:..:|..|:
  Fly   296 HLKAHKRTHTGEKPYVCTWEGCIWRFARSDELTRHYRK-HTGVKPFRCQLCTRSFSRSDHLSLHM 359

  Fly   388 KKH 390
            ::|
  Fly   360 RRH 362

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	25/66 (38%)
		zf-C2H2	311..333	CDD:278523	8/23 (35%)
		C2H2 Zn finger	313..333	CDD:275368	8/21 (38%)
		zf-H2C2_2	325..349	CDD:290200	12/25 (48%)
		C2H2 Zn finger	341..362	CDD:275368	8/22 (36%)
		zf-H2C2_2	353..377	CDD:290200	10/23 (43%)
		zf-C2H2	368..390	CDD:278523	7/21 (33%)
		C2H2 Zn finger	370..390	CDD:275368	6/19 (32%)
CG42741	NP_611747.2	COG5048	<273..>352	CDD:227381	31/79 (39%)
		zf-C2H2	280..304	CDD:278523	8/23 (35%)
		C2H2 Zn finger	282..304	CDD:275368	8/21 (38%)
		zf-H2C2_2	296..>313	CDD:290200	10/16 (63%)
		C2H2 Zn finger	312..334	CDD:275368	8/22 (36%)
		zf-H2C2_2	326..351	CDD:290200	11/25 (44%)
		C2H2 Zn finger	342..362	CDD:275368	6/19 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910