DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and CG8388

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_611075.1	Gene:	CG8388 / 36763	FlyBaseID:	FBgn0034062	Length:	572	Species:	Drosophila melanogaster

Alignment Length:	262	Identity:	59/262 - (22%)
Similarity:	102/262 - (38%)	Gaps:	55/262 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   244 PLKKCELTWPPP-TEQLQLELPHPN--PKLSPVLPHPQLQDYQTRRKNKARTAA-------TGGN 298
            |...||.|:|.. |.|..::|.|.|  .|:..|          ..:..:.|.|.       |||
  Fly   349 PCTHCEKTYPSQYTMQQHVKLVHLNLYAKICDV----------CGKSIRGREALARHMEEHTGG- 402

  Fly   299 ATPNLPQRNKDRYTCKFCGKVFPRSANLTRHLR-THTGE--QPYKCKYCERSFSISSNLQRHVRN 360
                 ||.   ...|..|..:......|.||:: .||.|  ||.:|::|.:........|.|::.
  Fly   403 -----PQA---AIKCHLCDSMLTTKYGLARHIKMMHTAENLQPMQCEFCLKICPSLQAHQHHIKY 459

  Fly   361 IHNKERPFKCEICERCFGQQTNLDRHLKKHESDAVSLSALSGVSERMHCIRRFCENPTEESYFEE 425
            .||..|..:|.:||:.|.:...|..|:..|..:.:....        ||.:.|..|....::.::
  Fly   460 THNTARSHQCPMCEKAFKRPNELKEHMTTHTGEVLYTCP--------HCPQTFNSNANMHAHRKK 516

  Fly   426 IRSFMGKVTQQQQQQQQQQQHDQQQQQHQSTATSASSSCSSSRDTPTSSHEEADHAPATSTADTA 490
            :          .:::.::.:|.:..:..:|....|    .|.|.| |.:.::....||.:.|.|:
  Fly   517 V----------HRKEWEENRHKRLNRSRKSDTIIA----VSVRKT-TETRQDGGLVPAEAIATTS 566

  Fly   491 AP 492
            :|
  Fly   567 SP 568

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	16/65 (25%)
		zf-C2H2	311..333	CDD:278523	5/22 (23%)
		C2H2 Zn finger	313..333	CDD:275368	5/20 (25%)
		zf-H2C2_2	325..349	CDD:290200	10/26 (38%)
		C2H2 Zn finger	341..362	CDD:275368	4/20 (20%)
		zf-H2C2_2	353..377	CDD:290200	8/23 (35%)
		zf-C2H2	368..390	CDD:278523	6/21 (29%)
		C2H2 Zn finger	370..390	CDD:275368	6/19 (32%)
CG8388	NP_611075.1	zf-AD	<21..77	CDD:285071
		C2H2 Zn finger	264..281	CDD:275368
		C2H2 Zn finger	289..309	CDD:275368
		C2H2 Zn finger	320..340	CDD:275368
		C2H2 Zn finger	350..369	CDD:275368	6/18 (33%)
		C2H2 Zn finger	440..461	CDD:275368	4/20 (20%)
		C2H2 Zn finger	469..489	CDD:275368	6/19 (32%)
		C2H2 Zn finger	497..515	CDD:275368	4/25 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910