DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and Sp6

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001102303.1	Gene:	Sp6 / 363672	RGDID:	1306768	Length:	376	Species:	Rattus norvegicus

Alignment Length:	341	Identity:	75/341 - (21%)
Similarity:	111/341 - (32%)	Gaps:	134/341 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   175 GGGGGGPPNAPPLTPPQCSIPAVHP----TLLEAMTKNLPLQYRNVFAGVLPGKVNS-------- 227
            |..|....:||..:||:..:..:..    |..||.....|||         ||::.|
  Rat     7 GSLGSQHTDAPHSSPPRLDLQPLQTYQGHTSPEAGDYPSPLQ---------PGELQSLPLGPEVD 62

  Fly   228 -------PAASSSPTGADFPFRHPLKK---CELTWP--------------PPTEQ---------- 258
                   |.|||..|..|.....||..   .:|..|              |.||.
  Rat    63 FSQGYELPGASSRVTCEDLESDSPLAPGPFSKLLQPDMSHHYESWFRPTHPGTEDGSWWDLHPGT 127

  Fly   259 LQLELPHPNPKLS------------------------PVLPHPQ--------------------L 279
            ..::|||....|:                        |..|||.                    |
  Rat   128 SWMDLPHTQGALTSPGHPGALQPALGGYVGDHQLCAPPPHPHPHHLLPAAGGQHLLGPPDGAKVL 192

  Fly   280 Q-------------DYQTRRKNKARTAATGGNAT----PNLPQ-------------RNKDRYTCK 314
            :             |...|.|...|:.......|    ||..:             :.|..:.|.
  Rat   193 EAAAPESQGLDSSLDAAARPKGSRRSVPRSSGQTVCRCPNCLEAERLGAPCGPDGGKKKHLHNCH 257

  Fly   315 F--CGKVFPRSANLTRHLRTHTGEQPYKCK--YCERSFSISSNLQRHVRNIHNKERPFKCEICER 375
            .  |||.:.::::|..|||.|:|::|:.|.  :|.:.|:.|..||||::. |...:.|.|.:|.|
  Rat   258 IPGCGKAYAKTSHLKAHLRWHSGDRPFVCNWLFCGKRFTRSDELQRHLQT-HTGTKKFPCAVCSR 321

  Fly   376 CFGQQTNLDRHLKKHE 391
            .|.:..:|.:|:|.||
  Rat   322 VFMRSDHLAKHMKTHE 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	23/83 (28%)
		zf-C2H2	311..333	CDD:278523	8/23 (35%)
		C2H2 Zn finger	313..333	CDD:275368	8/21 (38%)
		zf-H2C2_2	325..349	CDD:290200	9/25 (36%)
		C2H2 Zn finger	341..362	CDD:275368	8/22 (36%)
		zf-H2C2_2	353..377	CDD:290200	9/23 (39%)
		zf-C2H2	368..390	CDD:278523	8/21 (38%)
		C2H2 Zn finger	370..390	CDD:275368	7/19 (37%)
Sp6	NP_001102303.1	C2H2 Zn finger	259..278	CDD:275368	7/18 (39%)
		COG5048	<261..>336	CDD:227381	27/75 (36%)
		zf-H2C2_2	270..297	CDD:290200	10/26 (38%)
		C2H2 Zn finger	286..308	CDD:275368	8/22 (36%)
		zf-H2C2_2	300..323	CDD:290200	9/23 (39%)
		zf-C2H2	314..336	CDD:278523	8/21 (38%)
		C2H2 Zn finger	316..336	CDD:275368	7/19 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910