DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and Zfp143

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001012169.2	Gene:	Zfp143 / 361627	RGDID:	1305662	Length:	638	Species:	Rattus norvegicus

Alignment Length:	363	Identity:	76/363 - (20%)
Similarity:	111/363 - (30%)	Gaps:	136/363 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   279 LQDYQTRRKNKARTAATGGNATPNLPQRNKDRYTCKF---------------------------- 315
            ||.:.||             .||...|..:..:.||:
  Rat   218 LQGHATR-------------VTPKSQQSGEKAFRCKYDGCGKLYTTAHHLKVHERSHTGDRPYQC 269

  Fly   316 ----CGKVFPRSANLTRHLRTHTGEQPYKCK--YCERSFSISSNLQRHVRNIHNKERPFKCEI-- 372
                |||.|.....|..|.||||||:||:|.  .|.:||..|.:||:|:|. |..||||||.|
  Rat   270 EHSGCGKAFATGYGLKSHFRTHTGEKPYRCSEDNCTKSFKTSGDLQKHIRT-HTGERPFKCPIEG 333

  Fly   373 ------------------------------CERCFGQQTNLDRHLKKHESDAVSLSALSGVSERM 407
                                          |.|.|...||...|::.|..:...:..:.|..:|.
  Rat   334 CGRSFTTSNIRKVHIRTHTGERPYYCTEPGCGRAFASATNYKNHVRIHTGEKPYVCTVPGCDKRF 398

  Fly   408 ----------------------HC------------IRRFCENPTE------ESYFEEIRSFMGK 432
                                  ||            .:|...|.||      |::||..   .|:
  Rat   399 TEYSSLYKHHVVHTHSKPYNCNHCGKTYKQISTLAMHKRTAHNDTEPIEEEQEAFFEPP---PGQ 460

  Fly   433 VTQQQQQQQQQQQHDQQQQQHQSTATSASSSCSSSRDTPTSSHEEADHAPATSTADTAAPSSSRD 497
            .....:..|.......:.:...||..:..:....|:.....|.:...|. ..|.||..|..::..
  Rat   461 GDDVLKGSQITYVTGVEGEDIVSTQVATVTQSGLSQQVTLISQDGTQHV-NISQADMQAIGNTIT 524

  Fly   498 QEEEDSQPIMELKRTLTSKLFPTTTADSAMTTPQTTSI 535
            ...:|..||            ...|.|:.:::..|.|:
  Rat   525 MVTQDGTPI------------TVPTHDAVISSAGTHSV 550

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	28/96 (29%)
		zf-C2H2	311..333	CDD:278523	9/53 (17%)
		C2H2 Zn finger	313..333	CDD:275368	9/51 (18%)
		zf-H2C2_2	325..349	CDD:290200	13/25 (52%)
		C2H2 Zn finger	341..362	CDD:275368	9/22 (41%)
		zf-H2C2_2	353..377	CDD:290200	14/55 (25%)
		zf-C2H2	368..390	CDD:278523	10/53 (19%)
		C2H2 Zn finger	370..390	CDD:275368	8/51 (16%)
Zfp143	NP_001012169.2	SFP1	<207..292	CDD:227516	17/86 (20%)
		C2H2 Zn finger	239..261	CDD:275368	2/21 (10%)
		COG5048	<251..424	CDD:227381	42/173 (24%)
		C2H2 Zn finger	269..291	CDD:275368	7/21 (33%)
		C2H2 Zn finger	299..321	CDD:275368	9/22 (41%)
		C2H2 Zn finger	329..351	CDD:275368	2/21 (10%)
		C2H2 Zn finger	359..381	CDD:275368	6/21 (29%)
		C2H2 Zn finger	389..411	CDD:275368	2/21 (10%)
		C2H2 Zn finger	419..438	CDD:275368	2/18 (11%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910