DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and Zfp157

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_038945496.1	Gene:	Zfp157 / 360775	RGDID:	1359435	Length:	569	Species:	Rattus norvegicus

Alignment Length:	182	Identity:	51/182 - (28%)
Similarity:	75/182 - (41%)	Gaps:	35/182 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   311 YTCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKERPFKCEICER 375
            |.||.|||.|...:|||||.||||||:||:|:.|.:.||..|.|..|.|. |..|:|::||.|.:
  Rat   269 YVCKECGKAFFYKSNLTRHHRTHTGEKPYECEECRKGFSSKSELTSHHRT-HTGEKPYQCEECGK 332

  Fly   376 CFGQQTNLDRHLKKHESDAVSLSALSGVSERMHCIRRFCENPTEESYFEEIRSFMGKVTQQQQQQ 440
            .|..::.|..|.|.|..                      |.|.|....::...:...:|:.|:..
  Rat   333 AFYCKSTLRVHQKIHTG----------------------EKPYECKECQKSFYYKSTLTEHQRTH 375

  Fly   441 QQQQQHD------------QQQQQHQSTATSASSSCSSSRDTPTSSHEEADH 480
            ..::.::            |..:.|:.........|...|...:|..|...|
  Rat   376 TGEKPYECKDCGKAFFYKSQLTRHHRIHTGEKPYECEECRKAFSSKSELTAH 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	28/51 (55%)
		zf-C2H2	311..333	CDD:278523	13/21 (62%)
		C2H2 Zn finger	313..333	CDD:275368	12/19 (63%)
		zf-H2C2_2	325..349	CDD:290200	15/23 (65%)
		C2H2 Zn finger	341..362	CDD:275368	8/20 (40%)
		zf-H2C2_2	353..377	CDD:290200	9/23 (39%)
		zf-C2H2	368..390	CDD:278523	7/21 (33%)
		C2H2 Zn finger	370..390	CDD:275368	7/19 (37%)
Zfp157	XP_038945496.1	KRAB	5..65	CDD:214630
		C2H2 Zn finger	160..179	CDD:275368
		COG5048	183..529	CDD:227381	51/182 (28%)
		C2H2 Zn finger	187..207	CDD:275368
		C2H2 Zn finger	215..235	CDD:275368
		C2H2 Zn finger	243..263	CDD:275368
		C2H2 Zn finger	271..291	CDD:275368	12/19 (63%)
		C2H2 Zn finger	299..319	CDD:275368	8/20 (40%)
		C2H2 Zn finger	327..347	CDD:275368	7/19 (37%)
		C2H2 Zn finger	355..375	CDD:275368	2/19 (11%)
		C2H2 Zn finger	383..403	CDD:275368	2/19 (11%)
		C2H2 Zn finger	411..431	CDD:275368	5/17 (29%)
		C2H2 Zn finger	439..459	CDD:275368
		C2H2 Zn finger	467..487	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910