DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and Cf2

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001350854.1	Gene:	Cf2 / 33692	FlyBaseID:	FBgn0000286	Length:	537	Species:	Drosophila melanogaster

Alignment Length:	376	Identity:	84/376 - (22%)
Similarity:	143/376 - (38%)	Gaps:	105/376 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 LASSASVAATSSSSTSPTTTSATTTGRL------------QHQHSHQQHQTLNHHAKGKRRSSFD 91
            :.::|.:||...........:.|...:|            :.||..||.|..:||.:..::....
  Fly   183 ICTTAMLAAGQQGFMEQQEAAVTPDDQLPAMAPRDMRLTPEEQHHQQQLQAEHHHQQQHQQQQQQ 247

  Fly    92 QPLDLRLAHKRKTDLVDQGPMEDENSNLIMFASELAVAQQKEKELNNNHIAASLADLGFDMSRKM 156
            |.....|..:::.::.:|...:..:.:            |::::|..:.:|..:..|...:::
  Fly   248 QQQQQELLEQQQREMQEQAQQQQVHHH------------QQDQDLAGDQVALKVPPLTVKLNK-- 298

  Fly   157 LRALREGGAGGGGGGGGGGGGGGGPPNAPPLTPPQCSIPAVHPTLLEA--MTKNLPLQYRNVFAG 219
                   .|.||.                .::.||..|.....:|.::  :..::|:.......|
  Fly   299 -------NANGGA----------------IVSHPQVIIKEEPLSLSDSGDVVNSVPVYAIQANPG 340

  Fly   220 VLPGKVNSPAASSS---------PTGADFPFRHPLKKCELTWPPPTEQLQLELPHPNPKLSPVLP 275
            |       ||.:||         |.......||....|..|:..|               ..:..
  Fly   341 V-------PAPASSGVLVGTQTVPADLAHKIRHKCPDCPKTFKTP---------------GTLAM 383

  Fly   276 HPQLQDYQTRRKNKARTAATG-GNATPNLPQRNKDR-YTCKFCGKVFPRSANLTRHLRTHTGEQP 338
            |              |...|| .:|||      |:| |||.:|||.|.:|..|.:|.|.||||:|
  Fly   384 H--------------RKIHTGEADATP------KERPYTCSYCGKSFTQSNTLKQHTRIHTGEKP 428

  Fly   339 YKCKYCERSFSISSNLQRHVRNIHNKERPFKCEICERCFGQQTNLDRHLKK 389
            :.|.|||:|||:...|.:|:|. |..|:|:.|..|::.|.|::.|..|..|
  Fly   429 FHCGYCEKSFSVKDYLTKHIRT-HTGEKPYTCPYCDKRFTQRSALTVHTTK 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	30/63 (48%)
		zf-C2H2	311..333	CDD:278523	11/21 (52%)
		C2H2 Zn finger	313..333	CDD:275368	9/19 (47%)
		zf-H2C2_2	325..349	CDD:290200	13/23 (57%)
		C2H2 Zn finger	341..362	CDD:275368	10/20 (50%)
		zf-H2C2_2	353..377	CDD:290200	8/23 (35%)
		zf-C2H2	368..390	CDD:278523	7/22 (32%)
		C2H2 Zn finger	370..390	CDD:275368	7/20 (35%)
Cf2	NP_001350854.1	COG5048	<366..>473	CDD:227381	46/142 (32%)
		C2H2 Zn finger	368..388	CDD:275368	5/48 (10%)
		C2H2 Zn finger	403..423	CDD:275368	9/19 (47%)
		C2H2 Zn finger	431..451	CDD:275368	10/20 (50%)
		zf-H2C2_2	443..468	CDD:316026	9/25 (36%)
		C2H2 Zn finger	459..480	CDD:275368	7/20 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910