DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10348 and sp3b

DIOPT Version :9

Sequence 1:NP_001286059.1 Gene:CG10348 / 35132 FlyBaseID:FBgn0032707 Length:540 Species:Drosophila melanogaster
Sequence 2:XP_005165855.1 Gene:sp3b / 322961 ZFINID:ZDB-GENE-110815-3 Length:783 Species:Danio rerio


Alignment Length:474 Identity:104/474 - (21%)
Similarity:168/474 - (35%) Gaps:147/474 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 QGCVYPALG------LIPTSYISHVPYDLAS----SASVAATSSSS------TSPTTTSATTTGR 65
            ||.|...:|      |:|.:.:|:|  ||.|    .|...|||.::      |.||||::...| 
Zfish   321 QGQVVANMGLPGNITLVPINSLSNV--DLESLGLAGAQTIATSVTADGQLIMTGPTTTTSDNQG- 382

  Fly    66 LQHQHSHQQHQTLNHHAKGKRRSSFDQPLDLRLAHKRKTDLVDQGPMEDENSNLIMFASELAVAQ 130
                .|.:..::||  |.....::|..    .......|.|    |...:.:.::..|:.::...
Zfish   383 ----ESGKCTESLN--ANDANANAFVP----TTTSSTSTSL----PETIDGTGVLTQATAVSAGH 433

  Fly   131 QKEKELNNNH----------IAASLADLGFDMSRKMLRALREG---------------------- 163
            |....:..||          :.|..|| |...:.:.::.|..|                      
Zfish   434 QDLSYIQQNHTTGGEQVVQLLPAQTAD-GAAQTLQSVQLLNAGTFLIQAQTVSPTGQIQWQTFQV 497

  Fly   164 ------------GAGGGG--------------GGGGGGGGGGGPPNAPPLTPPQCSIPAVHPTLL 202
                        .|||..              |..|..|..|..||                  |
Zfish   498 QGVQNLQNLQLPAAGGVSSPQITLAPVQTLSLGQSGTTGALGQIPN------------------L 544

  Fly   203 EAMTKNLPLQYRNVFAGVLPGKVNSPAASSSPTGADFPFRHPLKKCELTWPPPTEQLQLELPHPN 267
            :.:|.|...||:.              ..::.:..|...:...:..:  ||..|.... :|.|  
Zfish   545 QTVTVNSVGQYQQ--------------DENTESHTDIQIKEEPESDD--WPNSTLSTS-DLAH-- 590

  Fly   268 PKLSPVLPHPQLQDYQTRRKNKARTAAT-------GGNATPNLPQRNKDRYTCKF--CGKVFPRS 323
              |...|....::......|...|.|.|       ||..:   ....|.::.|..  ||||:.::
Zfish   591 --LRVRLVEEDMEGTGQEGKRLRRVACTCPNCKEAGGRGS---SMGKKKQHICHIPGCGKVYGKT 650

  Fly   324 ANLTRHLRTHTGEQPYKC--KYCERSFSISSNLQRHVRNIHNKERPFKCEICERCFGQQTNLDRH 386
            ::|..|||.|:||:|:.|  .||.:.|:.|..|||| |..|..|:.|.|..|.:.|.:..:|.:|
Zfish   651 SHLRAHLRWHSGERPFICSWSYCGKRFTRSDELQRH-RRTHTGEKKFVCPECSKRFMRSDHLAKH 714

  Fly   387 LKKHESDAVSLSALSGVSE 405
            :|.|::.. .|::.:||.:
Zfish   715 IKTHQNKK-GLNSNTGVGQ 732

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10348NP_001286059.1 COG5048 300..>363 CDD:227381 24/66 (36%)
zf-C2H2 311..333 CDD:278523 9/23 (39%)
C2H2 Zn finger 313..333 CDD:275368 9/21 (43%)
zf-H2C2_2 325..349 CDD:290200 11/25 (44%)
C2H2 Zn finger 341..362 CDD:275368 10/22 (45%)
zf-H2C2_2 353..377 CDD:290200 10/23 (43%)
zf-C2H2 368..390 CDD:278523 7/21 (33%)
C2H2 Zn finger 370..390 CDD:275368 6/19 (32%)
sp3bXP_005165855.1 THAP 8..85 CDD:283206
C2H2 Zn finger 638..660 CDD:275368 9/21 (43%)
COG5048 <651..728 CDD:227381 29/78 (37%)
zf-C2H2 666..690 CDD:278523 10/24 (42%)
C2H2 Zn finger 668..690 CDD:275368 10/22 (45%)
zf-H2C2_2 682..705 CDD:290200 10/23 (43%)
zf-C2H2 696..718 CDD:278523 7/21 (33%)
C2H2 Zn finger 698..718 CDD:275368 6/19 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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