DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and Zfp112

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001100957.1	Gene:	Zfp112 / 308420	RGDID:	1305757	Length:	893	Species:	Rattus norvegicus

Alignment Length:	172	Identity:	59/172 - (34%)
Similarity:	79/172 - (45%)	Gaps:	45/172 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   311 YTCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKERPFKCEICER 375
            |.|..|||.|.|||.|..|.|.||||:||||:.|.:.||.||:||.|.| :|..|:|:|||.|.:
  Rat   565 YKCGECGKGFSRSAYLQGHQRVHTGEKPYKCEECGKGFSRSSHLQGHQR-VHTGEKPYKCEECGK 628

  Fly   376 CFGQQTNLDRHLKKHE--------------SDAVSLSALSGVSERMH----------CIRRFCEN 416
            .|....||..|.:.|.              |.|.:|.|    .||:|          |.:.|
  Rat   629 GFSWSFNLQIHQRVHTGEKPYKCGECGKGFSKASTLLA----HERIHTGEKPYQCHECGKNF--- 686

  Fly   417 PTEESYFEEIRS-----------FMGK-VTQQQQQQQQQQQH 446
             :::||.:..:|           ..|| .:|:...|..|:.|
  Rat   687 -SQKSYLQSHQSVHSGERPYICEVCGKGFSQRAYLQGHQRVH 727

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	29/51 (57%)
		zf-C2H2	311..333	CDD:278523	12/21 (57%)
		C2H2 Zn finger	313..333	CDD:275368	11/19 (58%)
		zf-H2C2_2	325..349	CDD:290200	12/23 (52%)
		C2H2 Zn finger	341..362	CDD:275368	10/20 (50%)
		zf-H2C2_2	353..377	CDD:290200	11/23 (48%)
		zf-C2H2	368..390	CDD:278523	8/21 (38%)
		C2H2 Zn finger	370..390	CDD:275368	7/19 (37%)
Zfp112	NP_001100957.1	KRAB	2..62	CDD:214630
		KRAB	2..41	CDD:279668
		C2H2 Zn finger	463..480	CDD:275368
		COG5048	508..852	CDD:227381	59/172 (34%)
		C2H2 Zn finger	511..531	CDD:275368
		zf-H2C2_2	523..548	CDD:290200
		C2H2 Zn finger	539..559	CDD:275368
		zf-H2C2_2	551..576	CDD:290200	6/10 (60%)
		C2H2 Zn finger	567..587	CDD:275368	11/19 (58%)
		zf-H2C2_2	579..604	CDD:290200	13/24 (54%)
		C2H2 Zn finger	595..615	CDD:275368	10/20 (50%)
		zf-H2C2_2	607..631	CDD:290200	11/24 (46%)
		C2H2 Zn finger	623..643	CDD:275368	7/19 (37%)
		zf-H2C2_2	635..659	CDD:290200	4/23 (17%)
		C2H2 Zn finger	651..671	CDD:275368	6/23 (26%)
		zf-H2C2_2	664..688	CDD:290200	7/31 (23%)
		C2H2 Zn finger	679..699	CDD:275368	5/23 (22%)
		C2H2 Zn finger	707..727	CDD:275368	5/19 (26%)
		C2H2 Zn finger	735..755	CDD:275368
		C2H2 Zn finger	763..783	CDD:275368
		C2H2 Zn finger	791..811	CDD:275368
		zf-H2C2_2	804..828	CDD:290200
		C2H2 Zn finger	819..839	CDD:275368
		zf-H2C2_2	831..854	CDD:290200
		C2H2 Zn finger	847..867	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910