DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and KLF15

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_011511045.1	Gene:	KLF15 / 28999	HGNCID:	14536	Length:	435	Species:	Homo sapiens

Alignment Length:	279	Identity:	75/279 - (26%)
Similarity:	108/279 - (38%)	Gaps:	83/279 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   160 LREGGAG--------GGGGGGGGGGGGGGP-PNAPPLTPPQCSIPAVHPTLLEAMTKNLPLQYRN 215
            |..|.:|        ||...||..|.|||| |:.|        ||.:             ||.:.
Human   201 LHPGSSGRERCSPPPGGASAGGAQGPGGGPTPDGP--------IPVL-------------LQIQP 244

  Fly   216 VFAGVLPGKVNSPAASSSPTGADFPFRHP--LKKCEL-------TW---PPPTEQLQLELPHPNP 268
            |           |....|.||...|.:.|  :|..:|       |:   |.......|.||....
Human   245 V-----------PVKQESGTGPASPGQAPENVKVAQLLVNIQGQTFALVPQVVPSSNLNLPSKFV 298

  Fly   269 KLSPVLPHPQLQDYQTRRKNKARTAATG-----------GNATPNLPQRNKDR-YTCKF--CGKV 319
            :::||             ...|:...:|           |...|..|.....: :.|.|  |.|:
Human   299 RIAPV-------------PIAAKPVGSGPLGPGPAGLLMGQKFPKNPAAELIKMHKCTFPGCSKM 350

  Fly   320 FPRSANLTRHLRTHTGEQPYKCKY--CERSFSISSNLQRHVRNIHNKERPFKCEICERCFGQQTN 382
            :.:|::|..|||.||||:|:.|.:  |...||.|..|.|| |..|:..:|::|.:||:.|.:..:
Human   351 YTKSSHLKAHLRRHTGEKPFACTWPGCGWRFSRSDELSRH-RRSHSGVKPYQCPVCEKKFARSDH 414

  Fly   383 LDRHLKKHESDAVSLSALS 401
            |.:|:|.|.....|.|..|
Human   415 LSKHIKVHRFPRSSRSVRS 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	25/67 (37%)
		zf-C2H2	311..333	CDD:278523	9/23 (39%)
		C2H2 Zn finger	313..333	CDD:275368	9/21 (43%)
		zf-H2C2_2	325..349	CDD:290200	11/25 (44%)
		C2H2 Zn finger	341..362	CDD:275368	9/22 (41%)
		zf-H2C2_2	353..377	CDD:290200	9/23 (39%)
		zf-C2H2	368..390	CDD:278523	7/21 (33%)
		C2H2 Zn finger	370..390	CDD:275368	7/19 (37%)
KLF15	XP_011511045.1	zf-C2H2	340..364	CDD:278523	9/23 (39%)
		zf-C2H2_8	342..421	CDD:292531	31/79 (39%)
		C2H2 Zn finger	342..364	CDD:275368	9/21 (43%)
		zf-H2C2_2	356..383	CDD:290200	12/26 (46%)
		C2H2 Zn finger	372..394	CDD:275368	9/22 (41%)
		zf-H2C2_2	386..411	CDD:290200	10/25 (40%)
		C2H2 Zn finger	402..422	CDD:275368	7/19 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910