DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and prz1

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_593073.1	Gene:	prz1 / 2541806	PomBaseID:	SPAC4G8.13c	Length:	681	Species:	Schizosaccharomyces pombe

Alignment Length:	284	Identity:	66/284 - (23%)
Similarity:	105/284 - (36%)	Gaps:	84/284 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   197 VHPTLLEAMTKNLPLQY-RNVFAGVLPGKVNSPAASSSPTGADFPFRHPLKKCEL---------- 250
            :.||.|    .|..|.| .|.|:|.....|...:.|.|.:|...| .:||.:.::
pombe   389 ISPTAL----SNSVLNYDSNNFSGTPQINVVPSSPSKSQSGPSLP-ANPLLQTDISITYSQSASP 448

  Fly   251 -TWPPPTEQLQLELPHPN---PKLSPVL-----------------PHPQL--------------- 279
             :..|...:...:|.:.|   |::||..                 |.|||
pombe   449 VSGQPAMNENSYDLQNANLCAPEMSPTYTARHRSNSAGSRFDAYEPIPQLYTHFSHSSECLSVNQ 513

  Fly   280 ---------------QDYQTRRKNKARTAATG---GNATPN-------LPQRNKDRYTCKF--CG 317
                           .||.:.|..:.|:.:..   ||.:.|       ...:::..|.|.|  |.
pombe   514 DTELLGKIENDNSKSNDYLSVRNTRPRSRSLNSLVGNKSENSSSSKAKSESKSQGNYVCTFAGCN 578

  Fly   318 KVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKERPFKCEICERCFGQQTN 382
            |.|.|:.||..|:.|||..:|::|..|::||:...:.:|| ..:|...:.|.|..|.:.|.:...
pombe   579 KRFTRAYNLKSHMNTHTNYRPFQCSICKKSFARQHDKRRH-EQLHTGIKAFACVTCNQRFARMDA 642

  Fly   383 LDRHLKKHESDAVSLSALSGVSER 406
            |:||.|..    |..:.|...:||
pombe   643 LNRHYKSE----VGQNCLRTATER 662

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	21/71 (30%)
		zf-C2H2	311..333	CDD:278523	10/23 (43%)
		C2H2 Zn finger	313..333	CDD:275368	9/21 (43%)
		zf-H2C2_2	325..349	CDD:290200	10/23 (43%)
		C2H2 Zn finger	341..362	CDD:275368	6/20 (30%)
		zf-H2C2_2	353..377	CDD:290200	6/23 (26%)
		zf-C2H2	368..390	CDD:278523	8/21 (38%)
		C2H2 Zn finger	370..390	CDD:275368	7/19 (37%)
prz1	NP_593073.1	COG5048	121..620	CDD:227381	53/236 (22%)
		zf-C2H2	570..594	CDD:278523	10/23 (43%)
		C2H2 Zn finger	577..594	CDD:275368	7/16 (44%)
		zf-H2C2_2	586..611	CDD:290200	11/24 (46%)
		C2H2 Zn finger	602..622	CDD:275368	6/20 (30%)
		zf-H2C2_2	616..639	CDD:290200	7/23 (30%)
		C2H2 Zn finger	630..648	CDD:275368	6/17 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24393
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100