DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and Zfp58

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001007576.1	Gene:	Zfp58 / 238693	MGIID:	99205	Length:	489	Species:	Mus musculus

Alignment Length:	156	Identity:	46/156 - (29%)
Similarity:	76/156 - (48%)	Gaps:	20/156 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   311 YTCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKERPFKCEICER 375
            :.|:.|||.|...:||:.|.|.||||:||||:.|.::|.|.|.|..|.| :|..|:|:|||.|.:
Mouse   106 FKCEECGKAFNNRSNLSEHKRIHTGEKPYKCEECGKAFRIRSKLSTHQR-VHTGEKPYKCEECGK 169

  Fly   376 CFGQQTNLDRHLKKHESDAVSLSALSGVSERMH----CIRRFCENPTEESYFEEIRSFMGKVTQQ 436
            .|...:||..|.:.|            ..|:.:    |.:.|   .|..:|:...::..||...:
Mouse   170 AFNSHSNLSEHKRIH------------TGEKPYKCEECGKAF---STRSTYYRHQKNHTGKKPYK 219

  Fly   437 QQQQQQQQQHDQQQQQHQSTATSASS 462
            .::..::..:....:.||...::..|
Mouse   220 CEECAKEFSYPSLLKVHQRIHSAEKS 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	24/51 (47%)
		zf-C2H2	311..333	CDD:278523	9/21 (43%)
		C2H2 Zn finger	313..333	CDD:275368	9/19 (47%)
		zf-H2C2_2	325..349	CDD:290200	13/23 (57%)
		C2H2 Zn finger	341..362	CDD:275368	8/20 (40%)
		zf-H2C2_2	353..377	CDD:290200	10/23 (43%)
		zf-C2H2	368..390	CDD:278523	8/21 (38%)
		C2H2 Zn finger	370..390	CDD:275368	7/19 (37%)
Zfp58	NP_001007576.1	KRAB	2..61	CDD:214630
		KRAB	2..41	CDD:279668
		C2H2 Zn finger	80..100	CDD:275368
		COG5048	106..489	CDD:227381	46/156 (29%)
		C2H2 Zn finger	108..128	CDD:275368	9/19 (47%)
		zf-H2C2_2	120..143	CDD:290200	13/22 (59%)
		C2H2 Zn finger	136..156	CDD:275368	8/20 (40%)
		zf-H2C2_2	149..173	CDD:290200	11/24 (46%)
		C2H2 Zn finger	164..184	CDD:275368	7/19 (37%)
		zf-H2C2_2	176..201	CDD:290200	7/39 (18%)
		C2H2 Zn finger	192..212	CDD:275368	4/22 (18%)
		C2H2 Zn finger	220..240	CDD:275368	2/19 (11%)
		C2H2 Zn finger	248..268	CDD:275368
		C2H2 Zn finger	276..296	CDD:275368
		C2H2 Zn finger	304..324	CDD:275368
		C2H2 Zn finger	332..352	CDD:275368
		zf-H2C2_2	344..369	CDD:290200
		C2H2 Zn finger	360..380	CDD:275368
		C2H2 Zn finger	388..408	CDD:275368
		C2H2 Zn finger	412..432	CDD:275368
		zf-H2C2_2	424..449	CDD:290200
		C2H2 Zn finger	440..460	CDD:275368
		C2H2 Zn finger	468..488	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910