DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG10348 and Wt1

DIOPT Version :9

Sequence 1:NP_001286059.1 Gene:CG10348 / 35132 FlyBaseID:FBgn0032707 Length:540 Species:Drosophila melanogaster
Sequence 2:NP_659032.3 Gene:Wt1 / 22431 MGIID:98968 Length:517 Species:Mus musculus


Alignment Length:454 Identity:98/454 - (21%)
Similarity:137/454 - (30%) Gaps:211/454 - (46%)


- Green bases have known domain annotations that are detailed below.


  Fly   148 LGFDMSRKMLRALREGGAGGGGGGGG-------------------------GGGGGGGPPNAPPL 187
            :|.|:  :.|.||....:..||||||                         |..||..||.|||.
Mouse    69 MGSDV--RDLNALLPAVSSLGGGGGGCGLPVSGAAQWAPVLDFAPPGASAYGSLGGPAPPPAPPP 131

  Fly   188 TPP--------------------QCSIPAVHPTLLEAMTKNLPLQYRNVFAGVL----------- 221
            .||                    ||         |.|.|    |.:...|.|..           
Mouse   132 PPPPPHSFIKQEPSWGGAEPHEEQC---------LSAFT----LHFSGQFTGTAGACRYGPFGPP 183

  Fly   222 -PGKVNSPAA-------------SSSPT------------------------GADFP---FRH-- 243
             |.:.:|..|             .|.||                        .|.||   |:|  
Mouse   184 PPSQASSGQARMFPNAPYLPSCLESQPTIRNQGYSTVTFDGAPSYGHTPSHHAAQFPNHSFKHED 248

  Fly   244 ------PLKKCELTWPPP-------------TEQLQLELPHPNPKL------------------- 270
                  .|.:.:.:.|||             ::.|.|..|:.:..|                   
Mouse   249 PMGQQGSLGEQQYSVPPPVYGCHTPTDSCTGSQALLLRTPYSSDNLYQMTSQLECMTWNQMNLGA 313

  Fly   271 --------------------------------SPVLPHPQ-----------LQDYQTRRKNKART 292
                                            :|:|...|           :||.: |....|.|
Mouse   314 TLKGMAAGSSSSVKWTEGQSNHGTGYESENHTAPILCGAQYRIHTHGVFRGIQDVR-RVSGVAPT 377

  Fly   293 AATGGNATPNLPQRNKDRYTCKF--CGKVFPRSANLTRHLRTHTGEQPYKC--KYCERSFSISSN 353
            .....:.|     ..|..:.|.:  |.|.:.:.::|..|.|.||||:||:|  |.|||.||.|..
Mouse   378 LVRSASET-----SEKRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQ 437

  Fly   354 LQRHVRNIHNKERPFKCEICERCFGQQTNLDRHLKKHESDAVSLSALSGVSERMH-CIRRFCEN 416
            |:||.|. |...:||:|:.|:|.|.:..    |||.|.......::....|.|.| |.::|..:
Mouse   438 LKRHQRR-HTGVKPFQCKTCQRKFSRSD----HLKTHTRTHTGKTSEKPFSCRWHSCQKKFARS 496

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10348NP_001286059.1 COG5048 300..>363 CDD:227381 26/66 (39%)
zf-C2H2 311..333 CDD:278523 6/23 (26%)
C2H2 Zn finger 313..333 CDD:275368 6/21 (29%)
zf-H2C2_2 325..349 CDD:290200 14/25 (56%)
C2H2 Zn finger 341..362 CDD:275368 12/22 (55%)
zf-H2C2_2 353..377 CDD:290200 10/23 (43%)
zf-C2H2 368..390 CDD:278523 8/21 (38%)
C2H2 Zn finger 370..390 CDD:275368 7/19 (37%)
Wt1NP_659032.3 WT1 69..389 CDD:280348 57/340 (17%)
COG5048 381..>509 CDD:227381 42/126 (33%)
C2H2 Zn finger 396..415 CDD:275368 5/18 (28%)
zf-H2C2_2 407..434 CDD:290200 15/26 (58%)
C2H2 Zn finger 423..445 CDD:275368 12/22 (55%)
zf-H2C2_2 438..462 CDD:290200 11/24 (46%)
C2H2 Zn finger 453..473 CDD:275368 8/23 (35%)
C2H2 Zn finger 484..506 CDD:275368 4/13 (31%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.