DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10348 and Klf2

DIOPT Version :9

Sequence 1:NP_001286059.1 Gene:CG10348 / 35132 FlyBaseID:FBgn0032707 Length:540 Species:Drosophila melanogaster
Sequence 2:NP_032478.2 Gene:Klf2 / 16598 MGIID:1342772 Length:354 Species:Mus musculus


Alignment Length:255 Identity:75/255 - (29%)
Similarity:103/255 - (40%) Gaps:66/255 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   158 RALREGGAGGGGGG--GGGGGGGGGPPNAPPLTPP-QCSIPAVHPTLLEAMTKNLPLQYRNVFAG 219
            |.|:..||.|..|.  .|..|....||:.|||:|. ...|||..|              ||.|  
Mouse   143 RGLKLEGAPGATGACMRGPAGRPPPPPDTPPLSPDGPLRIPASGP--------------RNPF-- 191

  Fly   220 VLPGKVNSPAASSSPT-GADFPFRHPLKKCELTWPPP--------------TEQLQLELPHPNPK 269
                   .|.....|: |...|..|        :.||              ...|.|..|.....
Mouse   192 -------PPPFGPGPSFGGPGPALH--------YGPPAPGAFGLFEDAAAAAAALGLAPPATRGL 241

  Fly   270 LSPVLPHPQLQDYQTRRKNKARTAATGGNATPNLPQRNKDRYTCKF--CGKVFPRSANLTRHLRT 332
            |:|  |...|:..:.:.|...|          :.|::....:||.:  |||.:.:|::|..||||
Mouse   242 LTP--PSSPLELLEAKPKRGRR----------SWPRKRAATHTCSYTNCGKTYTKSSHLKAHLRT 294

  Fly   333 HTGEQPYKCKY--CERSFSISSNLQRHVRNIHNKERPFKCEICERCFGQQTNLDRHLKKH 390
            ||||:||.|.:  |...|:.|..|.||.|. |...|||:|.:|:|.|.:..:|..|:|:|
Mouse   295 HTGEKPYHCNWEGCGWKFARSDELTRHYRK-HTGHRPFQCHLCDRAFSRSDHLALHMKRH 353

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10348NP_001286059.1 COG5048 300..>363 CDD:227381 26/66 (39%)
zf-C2H2 311..333 CDD:278523 10/23 (43%)
C2H2 Zn finger 313..333 CDD:275368 9/21 (43%)
zf-H2C2_2 325..349 CDD:290200 13/25 (52%)
C2H2 Zn finger 341..362 CDD:275368 8/22 (36%)
zf-H2C2_2 353..377 CDD:290200 11/23 (48%)
zf-C2H2 368..390 CDD:278523 8/21 (38%)
C2H2 Zn finger 370..390 CDD:275368 7/19 (37%)
Klf2NP_032478.2 9aaTAD. /evidence=ECO:0000250|UniProtKB:Q9Y5W3 42..50
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 52..111
Interaction with WWP1 110..267 38/166 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 145..208 24/85 (28%)
zf-C2H2 271..295 CDD:278523 10/23 (43%)
C2H2 Zn finger 273..295 CDD:275368 9/21 (43%)
COG5048 <276..>353 CDD:227381 34/77 (44%)
zf-C2H2 301..325 CDD:278523 9/24 (38%)
C2H2 Zn finger 303..325 CDD:275368 8/22 (36%)
zf-H2C2_2 317..342 CDD:290200 12/25 (48%)
C2H2 Zn finger 333..353 CDD:275368 7/19 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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