DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG10348 and Klf1

DIOPT Version :9

Sequence 1:NP_001286059.1 Gene:CG10348 / 35132 FlyBaseID:FBgn0032707 Length:540 Species:Drosophila melanogaster
Sequence 2:NP_034765.3 Gene:Klf1 / 16596 MGIID:1342771 Length:358 Species:Mus musculus


Alignment Length:253 Identity:76/253 - (30%)
Similarity:101/253 - (39%) Gaps:39/253 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly   169 GGGGGGGGGGGGPPN-------APPLTPPQCSIPAVHPTLLEAMTKNLPLQYRNVFAGVLPG--- 223
            |...||.|...||..       |.|...|....|.|.|.|...:.......|.:..||.:.|   
Mouse   113 GAYAGGPGLVTGPLGSEEHTSWAHPTPRPPAPEPFVAPALAPGLAPKAQPSYSDSRAGSVGGFFP 177

  Fly   224 --KVNSPAASSSPTG--ADFPFRHPLKKCELTWPPPTEQLQLELPHPNPKLSPVLPHPQLQ--DY 282
              .:..|||..:|.|  :.:|..:|.       |......||......|...|..|...|.  ..
Mouse   178 RAGLAVPAAPGAPYGLLSGYPALYPA-------PQYQGHFQLFRGLAAPSAGPTAPPSFLNCLGP 235

  Fly   283 QTRRKNKARTAATG------GNATP-----NLPQRNKDRYTC--KFCGKVFPRSANLTRHLRTHT 334
            .|.......||..|      |.|.|     .|..:.:..:||  :.|||.:.:|::|..||||||
Mouse   236 GTVATELGATAIAGDAGLSPGTAPPKRSRRTLAPKRQAAHTCGHEGCGKSYTKSSHLKAHLRTHT 300

  Fly   335 GEQPYKCKY--CERSFSISSNLQRHVRNIHNKERPFKCEICERCFGQQTNLDRHLKKH 390
            ||:||.|.:  |:..|:.|..|.||.|. |...|||.|.:|.|.|.:..:|..|:|:|
Mouse   301 GEKPYACSWDGCDWRFARSDELTRHYRK-HTGHRPFCCGLCPRAFSRSDHLALHMKRH 357

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10348NP_001286059.1 COG5048 300..>363 CDD:227381 27/71 (38%)
zf-C2H2 311..333 CDD:278523 10/23 (43%)
C2H2 Zn finger 313..333 CDD:275368 9/21 (43%)
zf-H2C2_2 325..349 CDD:290200 13/25 (52%)
C2H2 Zn finger 341..362 CDD:275368 8/22 (36%)
zf-H2C2_2 353..377 CDD:290200 11/23 (48%)
zf-C2H2 368..390 CDD:278523 8/21 (38%)
C2H2 Zn finger 370..390 CDD:275368 7/19 (37%)
Klf1NP_034765.3 EKLF_TAD1 22..>39 CDD:318931
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 35..69
EKLF_TAD2 63..85 CDD:318932
9aaTAD. /evidence=ECO:0000250|UniProtKB:Q13351 71..79
COG5048 <279..>357 CDD:227381 34/78 (44%)
C2H2 Zn finger 280..299 CDD:275368 8/18 (44%)
C2H2 Zn finger 307..329 CDD:275368 8/22 (36%)
C2H2 Zn finger 337..357 CDD:275368 7/19 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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