DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10348 and ZNF358

DIOPT Version :9

Sequence 1:NP_001286059.1 Gene:CG10348 / 35132 FlyBaseID:FBgn0032707 Length:540 Species:Drosophila melanogaster
Sequence 2:NP_060553.4 Gene:ZNF358 / 140467 HGNCID:16838 Length:568 Species:Homo sapiens


Alignment Length:256 Identity:71/256 - (27%)
Similarity:106/256 - (41%) Gaps:59/256 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   186 PLTPPQCSIPAVHPTLLEAMTKNLPLQYRNVFAGVLPGKVNSPAASSSPTGADFPFRHPLKKCEL 250
            |...|.|.....|...|        .|:|.:..|..|       ...:..|..|.:|..|.|...
Human   178 PYRCPDCGKSFSHGATL--------AQHRGIHTGARP-------YQCAACGKAFGWRSTLLKHRS 227

  Fly   251 TWPPPTEQLQLELPHPNPKLSPVLPHPQL--QDYQTR---RKNKARTAATG---GNA-TPNLPQR 306
            :...       |.||..|.......|..|  |..:|.   |.:|....|.|   |:| ..:|...
Human   228 SHSG-------EKPHHCPVCGKAFGHGSLLAQHLRTHGGPRPHKCPVCAKGFGQGSALLKHLRTH 285

  Fly   307 NKDR-YTCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVR----------- 359
            ..:| |.|..|||.|.:|:.|.:|.||||.|:||:|.:|.::|..|||||.|:|           
Human   286 TGERPYPCPQCGKAFGQSSALLQHQRTHTAERPYRCPHCGKAFGQSSNLQHHLRIHTGERPYACP 350

  Fly   360 ----------------NIHNKERPFKCEICERCFGQQTNLDRHLKKHESDAVSLSALSGVS 404
                            ::|:.|||::|::|.:.|||.::|.:|.:.||..|.:.:|.:..:
Human   351 HCSKAFGQSSALLQHLHVHSGERPYRCQLCGKAFGQASSLTKHKRVHEGAAAAAAAAAAAA 411

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10348NP_001286059.1 COG5048 300..>363 CDD:227381 28/90 (31%)
zf-C2H2 311..333 CDD:278523 10/21 (48%)
C2H2 Zn finger 313..333 CDD:275368 9/19 (47%)
zf-H2C2_2 325..349 CDD:290200 11/23 (48%)
C2H2 Zn finger 341..362 CDD:275368 10/47 (21%)
zf-H2C2_2 353..377 CDD:290200 11/50 (22%)
zf-C2H2 368..390 CDD:278523 7/21 (33%)
C2H2 Zn finger 370..390 CDD:275368 7/19 (37%)
ZNF358NP_060553.4 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..117
COG5048 <35..339 CDD:227381 55/182 (30%)
lambda-1 108..>174 CDD:212564
zf-C2H2 151..173 CDD:278523
C2H2 Zn finger 153..173 CDD:275368
zf-H2C2_2 166..190 CDD:290200 3/11 (27%)
C2H2 Zn finger 181..201 CDD:275368 6/27 (22%)
zf-H2C2_2 194..216 CDD:290200 6/36 (17%)
C2H2 Zn finger 209..229 CDD:275368 5/19 (26%)
zf-H2C2_2 222..244 CDD:290200 6/28 (21%)
C2H2 Zn finger 237..257 CDD:275368 4/19 (21%)
zf-H2C2_2 250..272 CDD:290200 5/21 (24%)
C2H2 Zn finger 265..285 CDD:275368 5/19 (26%)
zf-H2C2_2 277..300 CDD:290200 8/22 (36%)
zf-C2H2_8 292..370 CDD:292531 25/77 (32%)
C2H2 Zn finger 293..313 CDD:275368 9/19 (47%)
zf-H2C2_2 305..328 CDD:290200 11/22 (50%)
C2H2 Zn finger 321..341 CDD:275368 10/19 (53%)
zf-H2C2_2 333..356 CDD:290200 5/22 (23%)
C2H2 Zn finger 349..369 CDD:275368 0/19 (0%)
zf-H2C2_2 361..384 CDD:290200 6/22 (27%)
zf-C2H2 375..397 CDD:278523 7/21 (33%)
C2H2 Zn finger 377..397 CDD:275368 7/19 (37%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 448..568
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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