DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10348 and AgaP_AGAP009662

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_318706.4	Gene:	AgaP_AGAP009662 / 1279046	VectorBaseID:	AGAP009662	Length:	556	Species:	Anopheles gambiae

Alignment Length:	351	Identity:	85/351 - (24%)
Similarity:	131/351 - (37%)	Gaps:	97/351 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   230 ASSSPTGADFPFRHPLKKCELTWPPPTEQLQLELPHPNPKLSPVLPHPQLQDYQTRRKNKARTAA 294
            ||::|.|:.|       :|        .|..:.....:...|.:..|.:.|....:....|:...
Mosquito     1 ASATPVGSKF-------RC--------NQCNISFGSKSAHTSHMKSHAKQQQASEKLTAAAKLGE 50

  Fly   295 T---------GGNATPNLPQRNKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSI 350
            |         ||..:|..||  .|.|.|..|.|.|...|.|.||.||||||:|::|::|.:.||:
Mosquito    51 TTITASGGSGGGTGSPAGPQ--PDPYQCDVCKKTFAVPARLVRHYRTHTGERPFECEFCHKMFSV 113

  Fly   351 SSNLQRHVRNIHNKERPFKCEICERCFGQQTNLDRHLKKHESD------------------AVSL 397
            ..|||.| |.||.||||:|||||.|.|.....|.||::.|..:                  .:.:
Mosquito   114 KENLQVH-RRIHTKERPYKCEICGRAFEHSGKLHRHMRIHTGERPHKCNVCGKTFIQSGQLVIHM 177

  Fly   398 SALSG----------------------VSERMH----------CIRRFCENPTEESYFEEIRSFM 430
            ...:|                      |..|.|          |.|.|..|...:  ...::.:.
Mosquito   178 RTHTGEKPYKCPVEGCGKGFTCSKQLKVHSRTHTGEKPYHCDICFRDFGYNHVLK--LHRVQHYG 240

  Fly   431 GK------VTQQQQQQQQQQQH---------DQQQQQHQSTATSASSSCSSSRDTPTSSHEEAD- 479
            .|      ..:..:.:::.:.|         |.::....:.|:.|..:| ...|..||..|.:.
Mosquito   241 AKCYKCTICDETFKSKKEMEAHIKGHANELPDDEEAAAAAAASDAGGAC-KLEDVSTSGTEGSIK 304

  Fly   480 -HAPATSTADTAAPSSSRDQEEEDSQ 504
             .:.|...|:.|......|:|||:.:
Mosquito   305 LSSSALEGANEAGQQVGADEEEEEDE 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	30/62 (48%)
		zf-C2H2	311..333	CDD:278523	10/21 (48%)
		C2H2 Zn finger	313..333	CDD:275368	9/19 (47%)
		zf-H2C2_2	325..349	CDD:290200	12/23 (52%)
		C2H2 Zn finger	341..362	CDD:275368	9/20 (45%)
		zf-H2C2_2	353..377	CDD:290200	17/23 (74%)
		zf-C2H2	368..390	CDD:278523	10/21 (48%)
		C2H2 Zn finger	370..390	CDD:275368	9/19 (47%)
AgaP_AGAP009662	XP_318706.4	C2H2 Zn finger	12..32	CDD:275368	3/27 (11%)
		C2H2 Zn finger	76..96	CDD:275368	9/19 (47%)
		zf-H2C2_2	89..112	CDD:290200	12/22 (55%)
		C2H2 Zn finger	104..124	CDD:275368	9/20 (45%)
		zf-H2C2_2	116..141	CDD:290200	18/25 (72%)
		COG5048	<129..271	CDD:227381	22/143 (15%)
		C2H2 Zn finger	132..152	CDD:275368	9/19 (47%)
		zf-H2C2_2	147..169	CDD:290200	3/21 (14%)
		C2H2 Zn finger	160..180	CDD:275368	0/19 (0%)
		zf-H2C2_2	173..199	CDD:290200	1/25 (4%)
		C2H2 Zn finger	188..210	CDD:275368	2/21 (10%)
		zf-H2C2_2	203..227	CDD:290200	6/23 (26%)
		C2H2 Zn finger	218..238	CDD:275368	4/21 (19%)
		C2H2 Zn finger	246..266	CDD:275368	1/19 (5%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910