DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and AgaP_AGAP007883

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_317610.4	Gene:	AgaP_AGAP007883 / 1278073	VectorBaseID:	AGAP007883	Length:	493	Species:	Anopheles gambiae

Alignment Length:	155	Identity:	42/155 - (27%)
Similarity:	64/155 - (41%)	Gaps:	31/155 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   309 DRYTCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKERPFKCEIC 373
            :|.:|:.|||.|....:|..|:..|...:||||..|..:|.....|:.| :.:|.|:.||:|:||
Mosquito   292 ERVSCELCGKAFKYGQDLKVHMLQHEDPKPYKCDQCSSAFRFRGALRSH-KLLHQKDLPFRCDIC 355

  Fly   374 ERCFGQQTNLDRHLKKHESDAVSLSALSGVSERM--HCIRRFCENPTEESYFEEIR--------- 427
            .:.|....:|..|.:.|          |||.:.|  .|.|.|.   |:......::
Mosquito   356 AKYFRFANSLRVHKRLH----------SGVKQFMCEVCDREFA---TKAPLLRHMKVHDAGRELA 407

  Fly   428 ------SFMGKVTQQQQQQQQQQQH 446
                  .|..||..|..|.::...|
Mosquito   408 CGVCGAVFYKKVDLQIHQSKEHSAH 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	17/53 (32%)
		zf-C2H2	311..333	CDD:278523	7/21 (33%)
		C2H2 Zn finger	313..333	CDD:275368	7/19 (37%)
		zf-H2C2_2	325..349	CDD:290200	8/23 (35%)
		C2H2 Zn finger	341..362	CDD:275368	5/20 (25%)
		zf-H2C2_2	353..377	CDD:290200	9/23 (39%)
		zf-C2H2	368..390	CDD:278523	7/21 (33%)
		C2H2 Zn finger	370..390	CDD:275368	6/19 (32%)
AgaP_AGAP007883	XP_317610.4	C2H2 Zn finger	12..32	CDD:275368
		C2H2 Zn finger	40..60	CDD:275368
		zf-H2C2_2	53..75	CDD:290200
		C2H2 Zn finger	68..88	CDD:275368
		C2H2 Zn finger	95..113	CDD:275368
		C2H2 Zn finger	124..142	CDD:275368
		C2H2 Zn finger	149..168	CDD:275368
		C2H2 Zn finger	179..197	CDD:275368
		C2H2 Zn finger	205..223	CDD:275368
		C2H2 Zn finger	240..260	CDD:275368
		C2H2 Zn finger	268..287	CDD:275368
		C2H2 Zn finger	296..316	CDD:275368	7/19 (37%)
		C2H2 Zn finger	324..344	CDD:275368	5/20 (25%)
		C2H2 Zn finger	352..372	CDD:275368	6/19 (32%)
		C2H2 Zn finger	380..400	CDD:275368	4/22 (18%)
		C2H2 Zn finger	408..425	CDD:275368	4/16 (25%)
		C2H2 Zn finger	444..464	CDD:275368
		C2H2 Zn finger	472..489	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910